Results 71 to 80 of about 1,792 (176)

Reduced Dietary Protein Induces Changes in the Dental Proteome

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 2, Page 107-127, March 2026.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs, Christopher J. Percival, Natasha S. Vitek   +2 more
wiley   +1 more source

Epithelial-to-mesenchymal transition drives a pro-metastatic Golgi compaction process through scaffolding protein PAQR11 [PDF]

, 2017
Tumor cells gain metastatic capacity through a Golgi phosphoprotein 3-dependent (GOLPH3-dependent) Golgi membrane dispersal process that drives the budding and transport of secretory vesicles. Whether Golgi dispersal underlies the prometastatic vesicular
Alan R. Burns, Banerjee, Buschman, Chad J. Creighton, Daniel Ungar, Daniela Pankova, Don L. Gibbons, Feinstein, Hou-Fu Guo, Irodotos Michail Nikolaidis, Jonathan M. Kurie, Jonathon Roybal, Liu, Petry, Priyam Banerjee, Snapp, Stephen Ireland, Sundaramoorthy, Tomasz Zal, Xiaochao Tan, Xin Liu, Yadav, Yanbin Zhao, Yanzhuang Wang, Yongming Xue, Young-ho Ahn, Yu   +26 more
core   +1 more source

Single‐Cell RNAseq Identifies Heterogeneity in Myoblasts From Older Adults With Differences Related to Muscle Mass and Function

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Ageing is associated with the loss of muscle mass and function, with consequences for metabolic health, frailty and independence in later life. The aim of this study was to investigate the transcriptional heterogeneity of human proliferating muscle satellite/stem cells (myoblasts) from older adults and how this heterogeneity may ...
Mark A. Burton, Emma S. Garratt, Hanan Y. Sharkh, Matthew O. Hewitt, Elie Antoun, Leo D. Westbury, Elaine M. Dennison, Nicholas C. Harvey, Cyrus Cooper, Harnish P. Patel, Keith M. Godfrey, Karen A. Lillycrop   +11 more
wiley   +1 more source

Single nuclear‐spatial transcriptomic sequencing reveals distinct puncture‐induced cell subpopulations in the intervertebral disc of a rat model

Clinical and Translational Medicine, Volume 15, Issue 6, June 2025.
Summary of key events initiated from Stress Zone and related cell populations in puncture‐induced IVD degeneration. Abstract Objective We aim to investigate the spatiotemporal dynamics of intervertebral disc (IVD) cell subpopulations in IVD degeneration (IVDD).
Guoyan Liang, Jing Tan, Chong Chen, Yuying Liu, Yongyu Ye, Xiaolin Pan, Qiujian Zheng, Yunbing Chang, Feng‐Juan Lyu   +8 more
wiley   +1 more source

Wnt signaling exerts an antiproliferative effect on adult cardiac progenitor cells through IGFBP3. [PDF]

, 2011
RATIONALE: Recent work in animal models and humans has demonstrated the presence of organ-specific progenitor cells required for the regenerative capacity of the adult heart.
Bauer, Michael, Bayomy, Ahmad F, Biechele, Travis L, Conyers, Frank, Crapps, Dylan, Dong, Hanhua, Fine, Gabriel C, Force, Thomas, Guan, Jian, Han, Jung-Kyu, Liao, Annette, Liao, Ronglih, Moon, Randall T, Oikonomopoulos, Angelos, Sereti, Konstantina-Ioanna, Westerman, Karen   +15 more
core   +2 more sources

Temporal and partial inhibition of GLI1 in neural stem cells (NSCs) results in the early maturation of NSC derived oligodendrocytes in vitro. [PDF]

, 2019
BackgroundOligodendrocytes are a type of glial cells that synthesize the myelin sheath around the axons and are critical for the nerve conduction in the CNS.
Biswas, Sangita, Chechneva, Olga, Deng, Wenbin, Mayrhofer, Florian, Namchaiw, Poommaree, Wen, Han   +5 more
core  

Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery. [PDF]

, 2017
Neurite initiation is the first step in neuronal development and occurs spontaneously in soft tissue environments. Although the mechanisms regulating the morphology of migratory cells on rigid substrates in cell culture are widely known, how soft ...
Chang, Ting-Ya, Chang, Ya-Chu, Chen, Chen, Cheng, Pei-Lin, Guo, Chin-Lin, Lee, Min, Lu, Chi-Huan, Lu, Shao-Tzu, Wang, Aijun, Wang, De-Yao   +9 more
core   +2 more sources

The Diminution of R‐Loops Generated by LncRNA DSP‐AS1 Inhibits DSP Gene Transcription to Impede the Re‐Epithelialization During Diabetic Wound Healing

Advanced Science, Volume 12, Issue 12, March 27, 2025.
Down‐regulated LncRNA DSP‐AS1, the diminution of R‐loop formation, reduced Ten‐eleven translocation 3 (TET3) occupancy, inhibited DNA demethylation at the DSP promoter, and disrupted re‐epithelialization process proceed sequentially during delayed diabetic wound healing.
Chen Yang, Hong Lian, Hengli Luo, Chenlin Song, Jianghong Lin, Zhuoxian Liang, Yulin Yang, Xiaosi Hong, Shaohua Li, Yanbo Chen, Liangyan Wu, Li Yan, Sifan Chen, Meng Ren   +13 more
wiley   +1 more source

THE EFFECT OF RESISTANCE AND ENDURANCE EXERCISE TRAINING ON MUSCLE PROTEOME EXPRESSION IN HUMAN SKELETAL MUSCLE [PDF]

, 2012
To investigate the effect of resistance and endurance training on muscle proteome expression, samples of vastus lateralis from 10 physically active young men were analysed by 2-dimensional electrophoresis (2-DE) and matrix-assisted laser desorption ...
Chang Keun Kim, Hee Jeong Son, Hyo Jeong Kim   +2 more
core  

Aerobic capacity and muscle proteome: Insights from a mouse model

Experimental Physiology, Volume 110, Issue 2, Page 293-306, 1 February 2025.
Abstract We explored the association between aerobic capacity (AC) and the skeletal muscle proteome of McArdle (n = 10) and wild‐type (n = 8) mice, as models of intrinsically ‘low’ and ‘normal’ AC, respectively. AC was determined as total distance achieved in treadmill running until exhaustion.
Abel Plaza‐Florido, Alejandro Santos‐Lozano, Susana López‐Ortiz, Beatriz G. Gálvez, Joaquín Arenas, Miguel A. Martín, Pedro L. Valenzuela, Tomàs Pinós, Alejandro Lucia, Carmen Fiuza‐Luces   +9 more
wiley   +1 more source