Results 51 to 60 of about 1,792 (176)

Precise Similarity of Many Human Proteins to Proteins of Prokarya [PDF]

, 2007
Proteins originated in early forms of life and have long survived, because they have always been required. Some recognizably similar proteins are found in all sequence comparisons between species, no matter how distant, including prokaryotes and ...
Roy Britten
core   +2 more sources

Forschung für die Praxis: Bullöse Autoimmundermatosen unter Immuncheckpoint‐Inhibitoren [PDF]

J Dtsch Dermatol Ges
Zusammenfassung Immuncheckpoint‐Rezeptoren und ‐Liganden wie das cytotoxic T‐lymphocyte‐associated Protein 4 (CTLA‐4), programmed death‐1 (PD‐1) und ligand‐1 (PD‐L1) werden sowohl auf Immun‐ als auch auf nicht‐Immunzellen in großem Umfang exprimiert und dienen der Feinabstimmung des Aktivierungsniveaus von Immunzellen, wodurch Immunreaktionen ...
Prüßmann J, Prüßmann W, Sadik C.
europepmc   +2 more sources

LEPRE1 shapes a non‐flamed tumour immune landscape and predicts the prognosis in esophageal squamous cell carcinoma

, 2023
Clinical and Translational Medicine, Volume 13, Issue 11, November 2023.
Meng Liu, Yu Ma, Yunquan Guo, Yue Ma, Xinxin Bao, Xiaomei Lu   +5 more
wiley   +1 more source

Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivatives [PDF]

, 2009
BACKGROUND: Mouse embryonic stem (ES) cells remain pluripotent in vitro when grown in the presence of the cytokine Leukemia Inhibitory Factor (LIF).
Agapios Sachinidis, Bertrand Guillotin, Claire Saucourt, Frank Buchholz, Herbert Schulz, Hélène Bœuf, Jaak Vilo, Jurgen Hescheler, Li Ding, Marina Trouillas, Michael Doss, Norbert Huebner, Oliver Hummel, Raivo Kolde, Xavier Gauthereau   +14 more
core   +4 more sources

Dysferlin mediates the cytoprotective effects of TRAF2 following myocardial ischemia reperfusion injury [PDF]

, 2014
BACKGROUND: We have demonstrated that tumor necrosis factor (TNF) receptor‐associated factor 2 (TRAF2), a scaffolding protein common to TNF receptors 1 and 2, confers cytoprotection in the heart.
Barger, Philip M, Chambers, Kari, Evans, Sarah, Gao, Feng, Mann, Douglas L, Sivasubramanian, Natarajan, Topkara, Veli K, Tzeng, Huei-Ping   +7 more
core   +2 more sources

Seltene Form der Epidermolysis bullosa simplex mit homozygoter Mutation im Gen EXPH5

, 2023
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 21, Issue S2, Page 3-5, April 2023.
Henning Olbrich, Judith Fischer, Iakov Shimanovich   +2 more
wiley   +1 more source

Monoallelic Mutations in the Translation Initiation Codon of KLHL24 Cause Skin Fragility [PDF]

, 2016
The genetic basis of epidermolysis bullosa, a group of genetic disorders characterized by the mechanically induced formation of skin blisters, is largely known, but a number of cases still remain genetically unsolved.
Boerries, Melanie, Busch, Hauke, Castiglia, Daniele, Hannula-Jouppi, Katariina, Has, Cristina, Hausser, Ingrid, He, Yinghong, Heikkilä, Hannele, Kiritsi, Dimitra, Leppert, Juna, Maier, Kristin, Schwieger-Briel, Agnes, Tasanen, Kaisa, Theiler, Martin, Weibel, Lisa, Zambruno, Giovanna   +15 more
core   +1 more source

Characterization of the most frequent ATP7B mutation causing Wilson disease in hepatocytes from patient induced pluripotent stem cells [PDF]

, 2018
H1069Q substitution represents the most frequent mutation of the copper transporter ATP7B causing Wilson disease in Caucasian population. ATP7B localizes to the Golgi complex in hepatocytes but moves in response to copper overload to the endo-lysosomal ...
Allocca, Simona, Bonatti, Stefano, Ciano, Michela, Gallo, Maria, Iorio, Raffaele, Musto, Anna, Parisi, Silvia, Perone, Lucia, Polishchuk, Elena V, Polishchuk, Roman S, Ranucci, Giusy   +10 more
core   +2 more sources

Identification of calgranulin B interacting proteins and network analysis in gastrointestinal cancer cells.

PLoS ONE, 2017
Calgranulin B is known to be involved in tumor development, but the underlying molecular mechanism is not clear. To gain insight into possible roles of calgranulin B, we screened for calgranulin B-interacting molecules in the SNU-484 gastric cancer and ...
Kyung-Hee Kim, Seung-Gu Yeo, Byong Chul Yoo, Jae Kyung Myung   +3 more
doaj   +1 more source

Defenders and Challengers of Endothelial Barrier Function

Frontiers in Immunology, 2017
Regulated vascular permeability is an essential feature of normal physiology and its dysfunction is associated with major human diseases ranging from cancer to inflammation and ischemic heart diseases. Integrity of endothelial cells also play a prominent
Nader Rahimi
doaj   +1 more source