Results 91 to 100 of about 35,595 (240)

Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis

Scientific Reports, 2017
Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder resulting from mutations in the dystrophin gene. The mdx/utrn −/− mouse, lacking in both dystrophin and its autosomal homologue utrophin, is commonly used to model the clinical symptoms of
Hung-Chih Chen, Yu-Feng Chin, David J. Lundy, Chung-Tiang Liang, Ya-Hui Chi, Paolin Kuo, Patrick C. H. Hsieh   +6 more
doaj   +1 more source

Direct visualization of the dystrophin network on skeletal muscle fiber membrane. [PDF]

, 1992
Volker Straub, Reginald E. Bittner, J. Léger, Thomas Voit   +3 more
openalex   +1 more source

The subcellular distribution of dystrophin in mouse skeletal, cardiac, and smooth muscle. [PDF]

, 1991
T J Byers, Louis M. Kunkel, Simon C. Watkins   +2 more
openalex   +1 more source

Non-isotopic analysis of single strand conformation polymorphism (SSCP) in the exon 13 region of the human dystrophin gene. [PDF]

, 1993
Uwe Lenk, R. Hanke, U Kraft, K Grade, Ingrid Grunewald, Andreas Speer   +5 more
openalex   +1 more source

Systemic delivery of an AAV9 exon-skipping vector significantly improves or prevents features of Duchenne muscular dystrophy in the Dup2 mouse

Molecular Therapy: Methods & Clinical Development, 2022
Duchenne muscular dystrophy (DMD) is typically caused by mutations that disrupt the DMD reading frame, but nonsense mutations in the 5′ part of the gene induce utilization of an internal ribosomal entry site (IRES) in exon 5, driving expression of a ...
Nicolas Wein, Tatyana A. Vetter, Adeline Vulin, Tabatha R. Simmons, Emma C. Frair, Adrienne J. Bradley, Liubov V. Gushchina, Camila F. Almeida, Nianyuan Huang, Daniel Lesman, Dhanarajan Rajakumar, Robert B. Weiss, Kevin M. Flanigan   +12 more
doaj  

Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD

Molecular Therapy: Nucleic Acids, 2022
Duchenne muscular dystrophy (DMD) is the most prevalent inherited myopathy affecting children, caused by genetic loss of the gene encoding the dystrophin protein.
Britt Hanson, Sofia Stenler, Nina Ahlskog, Katarzyna Chwalenia, Nenad Svrzikapa, Anna M.L. Coenen-Stass, Marc S. Weinberg, Matthew J.A. Wood, Thomas C. Roberts   +8 more
doaj  

Identification of a novel first exon in the human dystrophin gene and of a new promoter located more than 500 kb upstream of the nearest known promoter. [PDF]

, 1994
Hisahide Nishio, Yasuhiro Takeshima, Naoko Narita, Hiroshi Yanagawa, Yoshiyuki Suzuki, Yoshihiro Ishikawa, Yoshihiro Ishikawa, Rumi Minami, Hajime Nakamura, Masafumi Matsuo   +9 more
openalex   +1 more source

Localization of dystrophin gene transcripts during mouse embryogenesis. [PDF]

, 1992
Denis Houzelstein, Gary E. Lyons, Jeffrey S. Chamberlain, M Buckingham   +3 more
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Dystrophin is phosphorylated by endogenous protein kinases [PDF]

, 1993
Monica De Luise, Cristina Presotto, L. Senter, Romeo Betto, Stefania Ceoldo, Sandra Furlan, Sergio Salvatori, Roger A. Sabbadini, G. Salviati   +8 more
openalex   +1 more source

Isolation and characterization of different C-terminal fragments of dystrophin expressed in Escherichia coli [PDF]

, 1992
R E Milner, Jody L. Busaan, Marek Michalak   +2 more
openalex   +1 more source