Results 91 to 100 of about 48,181 (245)

Dystrophin S3059 phosphorylation partially attenuates denervation atrophy in mouse tibialis anterior muscles

Physiological Reports
The dystrophin protein has well‐characterized roles in force transmission and maintaining membrane integrity during muscle contraction. Studies have reported decreased expression of dystrophin in atrophying muscles during wasting conditions, and that ...
Kristy Swiderski, Timur Naim, Jennifer Trieu, Annabel Chee, Marco J. Herold, Andrew J. Kueh, Craig A. Goodman, Paul Gregorevic, Gordon S. Lynch   +8 more
doaj   +1 more source

Genetic modifiers of ambulation in the cooperative international Neuromuscular Research Group Duchenne natural history study [PDF]

, 2015
OBJECTIVE: We studied the effects of LTBP4 and SPP1 polymorphisms on age at loss of ambulation (LoA) in a multiethnic Duchenne muscular dystrophy (DMD) cohort.
Andreone, Luz, Bello, Luca, Cnaan, Avital, Cooperative International Neuromuscular Research Group Investigators, Dubrovsky, Alberto, Duong, Tina, Gordish Dressman, Heather, Henricson, Erik K., Hoffman, Eric P., Kesari, Akanchha, McDonald, Craig M., Morgenroth, Lauren P., Pegoraro, Elena, Punetha, Jaya   +13 more
core   +1 more source

Advances in Stem Cell Modeling of Dystrophin-Associated Disease: Implications for the Wider World of Dilated Cardiomyopathy [PDF]

, 2020
Josè Manuel Pioner, Alessandra Fornaro, Raffaele Coppini, Nicole Ceschia, Leonardo Sacconi, Maria Alice Donati, Silvia Favilli, Corrado Poggesi, Iacopo Olivotto, Cecilia Ferrantini   +9 more
openalex   +1 more source

Thermodynamic stability, unfolding kinetics, and aggregation of the N-terminal actin-binding domains of utrophin and dystrophin. [PDF]

, 2012
Muscular dystrophy (MD) is the most common genetic lethal disorder in children. Mutations in dystrophin trigger the most common form of MD, Duchenne, and its allelic variant Becker MD.
Aaartsma-Rus, Ahmad, Badorff, Barghorn, Belli, Blake, Blake, Chamberlain, Chenna, Chi, Cotton, Courdier-Fruh, Daragan, Deconinck, Deconinck, Delaglio, Deol, Ebihara, Emery, Ervasti, Espargaró, Fairclough, Fisher, Foster, Galkin, Galkin, Gilbert, Gimona, Grady, Gramolini, Greenfield, Gregorevic, Gregorevic, Hamed, Helliwell, Henderson, Henderson, Hoffman, Ishikawa-Sakurai, Ito, Kahana, Karpati, Keep, Khurana, Khurana, Kim, Klunk, Knuesel, Krishna, Lakowicz, Le Rumeur, Legardinier, Lehman, Levine-III, Li, Lin, Love, Love, Mallela, Matsumura, Mayer, Mirza, Miura, Moores, Muir, Muntoni, Myers, Nagarajan, Norwood, Odom, Odom, Ohlendieck, Orlova, Park, Parsell, Pastoret, Pearce, Phelps, Pons, Prior, Prior, Prochniewicz, Rafael, Rafael, Roberts, Roberts, Roberts, Ruschak, Ruszczak, Rybakova, Rybakova, Santoro, Santoro, Scott, Shatsky, Sieb, Singh, Singh, Sitnik, Sonnemann, Squire, Sutherland-Smith, Tanabe, Tinsley, Tinsley, Tinsley, van Deutekom, Wakefield, Wang, Wang, Winder, Winder   +111 more
core   +1 more source

Reviewer #3 (Public Review): Binding of LncRNA-DACH1 to dystrophin impairs the membrane trafficking of Nav1.5 protein and increases ventricular arrhythmia susceptibility

, 2023
Henry M. Colecraft
openalex   +1 more source

Live‐imaging of revertant and therapeutically restored dystrophin in the Dmd^EGFP‐mdx mouse model for Duchenne muscular dystrophy [PDF]

, 2020
Mina Petkova, Amalia Stantzou, A. Morin, Olga N. Petrova, Susanne Morales-Gonzalez, Franziska Seifert, J. Bellec-Dyèvre, Tudor Manoliu, Aurélie Goyenvalle, Laurynn Garcia, Isabelle Richard, Corinne Laplace‐Builhé, Markus Schuelke, Helge Amthor   +13 more
openalex   +1 more source

Collagen XV preserves heart function and protects from pathological remodelling after myocardial infarction

The FEBS Journal, EarlyView.
The damage caused by myocardial infarction is exacerbated in the absence of collagen XV and leads to pathological remodelling and more severe left ventricle dysfunction (left panel) compared with the wild‐type littermates. These changes are accompanied by a wide‐ranging impact, including phenotypical (middle panel) and molecular (right panel) changes ...
Sanna‐Maria Karppinen, Miki Aho, Zoltan Szabo, Johanna Magga, Laura Vainio, Erhe Gao, Paul Janmey, Lauri Eklund, Karolina Rasi, Ilkka Miinalainen, Lynn Y. Sakai, Lasse Pakanen, Heikki Huikuri, Juhani Junttila, Risto Kerkelä, Taina Pihlajaniemi   +15 more
wiley   +1 more source

Myocellular adaptations to short‐term weighted wheel‐running exercise are largely conserved during C26‐tumour induction in male and female mice

Experimental Physiology, EarlyView.
Abstract This study investigated whether performing a translatable murine model of concurrent training after tumour induction affects adaptations in juvenile male and female tumour‐bearing mice. Male and female Balb/c mice were injected bilaterally with colon‐26 adenocarcinoma (C26) cells or PBS at 8 weeks of age.
Stavroula Tsitkanou, Pieter Koopmans, Calvin Peterson, Ana Regina Cabrera, Ruqaiza Muhyudin, Francielly Morena, Sabin Khadgi, Eleanor R. Schrems, Tyrone A. Washington, Kevin A. Murach, Nicholas P. Greene   +10 more
wiley   +1 more source

Duchenne muscular dystrophy treatment with lentiviral vector containing mini‐dystrophin gene in vivo

MedComm
Duchenne muscular dystrophy (DMD) is an incurable X‐linked recessive genetic disease caused by mutations in the dystrophin gene. Many researchers aim to restore truncated dystrophin via viral vectors.
Xiaoyu Wang, Yanghui Zhu, Taiqing Liu, Lingyan Zhou, Yunhai Fu, Jinhua Zhao, Yinqi Li, Yeteng Zheng, Xiaodong Yang, Xiangjie Di, Yang Yang, Zhiyao He   +11 more
doaj   +1 more source

Biglycan : a multivalent proteoglycan providing structure and signals [PDF]

, 2013
Research over the past few years has provided fascinating results indicating that biglycan, besides being a ubiquitous structural component of the extracellular matrix (ECM), may act as a signaling molecule.
Năstase, Mădălina-Viviana, Schäfer, Liliana, Young, Marian F.   +2 more
core