Results 121 to 130 of about 52,918 (243)
Clinical Pharmacology &Therapeutics, EarlyView.Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin +6 more
wiley +1 more source
Contributions to Plasma Physics, EarlyView.ABSTRACT The properties of plasmas in the low‐density limit are described by virial expansions. Analytical expressions are known for the lowest virial coefficients from Green's function approaches. Recently, accurate path‐integral Monte Carlo (PIMC) simulations were performed for the hydrogen plasma at low densities by Filinov and Bonitz (Phys. Rev.
Gerd Röpke +3 more
wiley +1 more source
La Norvège et la Suisse face à la construction européenne [PDF]
, 2011 International audienceLes refus d'adhésions successifs de la Suisse et de la Norvège à l'UE ne s'expliquent pas seulement par des intérêts économiques divergents.
Olivier, Jean-Marc
core +1 more source
Deep Underground Science and Engineering, EarlyView.This article aims to investigate the dynamic fracture response of fractured tunnel models under zero geological stress through physical experiments and numerical simulations. It further simulates the dynamic fracture characteristics of fractured tunnel models under geological stress ranging from 0 to 2.5 MPa using the numerical software AUTODYN ...
Peng Ying +7 more
wiley +1 more source
The Bulletin of the Ecological Society of America, EarlyView.
Shersingh Joseph Tumber‐Dávila +5 more
wiley +1 more source
Deep Underground Science and Engineering, EarlyView.This study investigates the blast‐induced rock damage patterns under different cut‐hole layouts and ground stress conditions through numerical simulations and field tests. The findings in this study provide valuable insights for similar underground engineering applications.
Junjie Zhao +5 more
wiley +1 more source
Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle
Developmental Dynamics, EarlyView.Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell +3 more
wiley +1 more source
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.The motivation behind the development of the new lithium salt LiDFFSI is to combine the advantages of both LiFSI and LiDFSI salts. LiDFFSI offers high ionic conductivity and enhanced compatibility with aluminum current collectors. Additionally, it promotes the formation of a conductive SEI layer rich in LiF and LiH, which contributes to an extended ...
Lorena García +9 more
wiley +1 more source
Flavour and Fragrance Journal, EarlyView.The essential oils of Piper nigrum show marked chemical and biological variation across fruit maturation stages. Ripe fruits yield oils with the strongest antioxidant and cytotoxic activities, demonstrating that maturation directly modulates volatile composition and enhances the bioactive potential of this aromatic species.
Marcio Marcelo da Siva Pessoa +6 more
wiley +1 more source
Food Safety and Health, EarlyView.Evaluation of the efficacy of selected dipping solutions on fresh chicken meat shelf life. Samples treated with nisin and EDTA combinations, followed by chilled storage. The effectiveness of these interventions was assessed through bacteriological, sensory, and physicochemical (pH) deterioration criteria.
Mohamed M. Eltanty +5 more
wiley +1 more source