Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche +8 more
wiley +1 more source
Predictive value of FeNO, eosinophils, and IgE for airway hyperresponsiveness in children with chronic cough: a cross-sectional study. [PDF]
Bian J +5 more
europepmc +1 more source
Environmentally adjusted productivity growth and shadow prices for dairy farms
Abstract We estimate the environmentally adjusted productivity growth and shadow price for Ontario dairy farms. We use an input‐oriented directional distance function and farm‐level data from 2000 to 2020. First, we find that while GHG emissions per cow increase with higher milk yields, emission intensity decreases as milk yield per cow increases.
Bibek Dahal +2 more
wiley +1 more source
Exploring Primary and Interaction Effects of Minor Physical Anomalies: Development and Validation of Prediction Models Using Explainable Machine Learning Algorithms for Early-Onset Schizophrenia. [PDF]
Lin CW +11 more
europepmc +1 more source
Abstract Automated insect identification systems hold significant value for biodiversity monitoring, pest management, citizen science initiatives and systematic studies, particularly in an era of declining expertise in insect taxonomy. However, current deep learning approaches often rely on standardized specimen photos from limited‐angles and ...
Xinkai Wang +10 more
wiley +1 more source
Nanoencapsulation of Eucalyptus Essential Oils via Box-Behnken Design: Phytochemical Profiling and Enhanced Antibacterial and Antibiofilm Efficacy. [PDF]
Beba Pozharani L +9 more
europepmc +1 more source
ABSTRACT Objective To evaluate the frequency and quantity of residual cement after cementation of monolithic zirconia crowns with glass ionomer or resin composite cement on customized ceramic abutments, following different intraoral retention times. The influence of margin location, quadrant and implant region was also assessed.
Maria Weinreuter +4 more
wiley +1 more source
Antimicrobial Susceptibility Patterns and Outcomes of Neonatal Early-Onset Sepsis over a Decade: Implications for Empirical Therapy in a Tertiary NICU. [PDF]
Muszyńska-Radska K +2 more
europepmc +1 more source
Analysis of Phthalates in Food Contact Materials:Selected samples from the Norwegian Market [PDF]
Jensen, Lisbeth Krüger +1 more
core
Association between initial empirical antibiotic therapy and necrotizing enterocolitis in very preterm infants at different risk for early-onset sepsis: a multicenter cohort study. [PDF]
Li Z +9 more
europepmc +1 more source

