Results 251 to 260 of about 25,003,793 (315)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Enhancing the therapeutic efficacy of dexamethasone for oral ulcers through adhesive gelatin hydrogel-based nano-delivery system. [PDF]

Mater Today Bio
Tang Q, Chen Y, Liu M, Ning X, Chen Q, He S.   +5 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Finance, Administration, and Operations newsletter June 2025

core  

Long-Term Consumption of Hyaluronan Increases Its Endogenous Levels Correlating with Attenuated Acute Alcohol-Induced Liver Injury. [PDF]

Int J Mol Sci
Zeng Q, Zheng Z, Sun T, Wang J, Fang J, Shao H, Liu F, Ling P.   +7 more
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Finance, Administration, and Operations newsletter February 2025

core  

Pneumococcal Endopeptidase O Attenuates Colitis by Inhibiting the Macrophage-CCL2 Axis and Reshaping Gut Microbiota. [PDF]

J Inflamm Res
Wang H, Shao S, Peng Y, Xu W, Zhang J, Liu X, Bian X, Huang K, Zhang X.   +8 more
europepmc   +1 more source

Early immune responses to intradermal lipopolysaccharide in healthy volunteers: prednisolone's impact on TLR4-mediated inflammation. [PDF]

Front Immunol
Buters TP, de Bruin DT, Hameeteman PW, Ten Voorde W, Grievink HW, Osse M, de Kam ML, Damman J, van den Bosch TPP, Neubert E, Rissmann R, Burggraaf J, Klarenbeek N, Jansen MAA, Moerland M.   +14 more
europepmc   +1 more source

Lineage infidelity in FH-deficient RCC with secondary somatic alterations: a case report and implications for diagnosis and treatment. [PDF]

Ther Adv Med Oncol
Zhao J, Allison DB, Genovese G, Rock S, Spies N, Hensley M, Khegai G, Makeeva A, Melikhova D, Bedniagin L, Hensley PJ, Myint ZW, Msaouel P.   +12 more
europepmc   +1 more source