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DDR1 regulates the stabilization of cell surface E‐cadherin and E‐cadherin‐mediated cell aggregation
Journal of Cellular Physiology, 2010AbstractThe stabilization of cell surface E‐cadherin is important for the maintenance of apical junction complexes and epithelial polarity. Previously, we reported that discoidin domain receptor 1 (DDR1) forms a complex with E‐cadherin at adhesive contacts; however, the regulatory role of DDR1 in the stabilization of cell surface E‐cadherin and E ...
Rajalakshmanan, Eswaramoorthy +7 more
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European Journal of Cancer, 2003
Loss of E-cadherin (E-cad) has been associated with progression and poor survival in nasopharyngeal carcinoma (NPC). In this study, we investigated the role of methylation on E-cad inactivation in NPC cell lines, as well as in NPC tissue samples. Using 6 NPC cell lines, we found that methylation of the E-cad 5' CpG island promoter region was correlated
Nicholls, JM +9 more
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Loss of E-cadherin (E-cad) has been associated with progression and poor survival in nasopharyngeal carcinoma (NPC). In this study, we investigated the role of methylation on E-cad inactivation in NPC cell lines, as well as in NPC tissue samples. Using 6 NPC cell lines, we found that methylation of the E-cad 5' CpG island promoter region was correlated
Nicholls, JM +9 more
openaire +4 more sources
A bigger picture: classical cadherins and the dynamic actin cytoskeleton
Nature Reviews Molecular Cell Biology, 2012Aparna Ratheesh, Alpha Yap
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