Results 21 to 30 of about 149,948 (280)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Lagrangian Volume Deformations around Simulated Galaxies [PDF]
, 2015 We present a detailed analysis of the local evolution of 206 Lagrangian Volumes (LVs) selected at high redshift around galaxy seeds, identified in a large-volume $\Lambda$ cold dark matter ($\Lambda$CDM) hydrodynamical simulation.
Domínguez-Tenreiro, R. +3 more
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
As raízes medievais do pensamento moderno. [Reseña] [PDF]
, 2003 Reseña de: Alessandro GHISALBERTI, As raízes medievais do pensamento moderno, presentación de Mauro de Medeiros Keller, Instituto Brasileiro de Filosofía e Ciencia «Raymundo Lulio»-EDIPUCRS («Filosofía», 131), Porto Alegre 2001, 109 ...
Saranyana, J.I. (Josep Ignasi)
core
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Modelo/s de coste para la preservación de los datos científicos en la e-ciencia [PDF]
, 2010 Within the framework of the e-science, preservation of scientific data is an essential task for achieving robust and sustainable information cyberinfraestructure.
Pérez González, Lourdes
core
The stellar spheroid, the disk, and the dynamics of the cosmic web [PDF]
, 2015 Astrophysical Journal Letters 800.2 (2015): L30 reproduced by permission of the AASModels of the advanced stages of gravitational instability predict that baryons that form the stellar populations of current galaxies at z = 0 displayed a web-like ...
Brook, C. B. +5 more
core +2 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
O picarismo n"O Desgraciado Amante Peralvilho" [PDF]
, 2009 “O Desgraciado Amante Peralvilho”, de Pires de Rebelo, nos invita a reanalizar su esquema narrativo y a plantear la incursión del autor en la picaresca.
Comino Fernández de Cañete, Carmen María
core +1 more source