Results 21 to 30 of about 21,995,573 (301)
Entre Ciencia e Ingeniería, 2007 El establecimiento de la Política Nacional de Ciencia Tecnología e Innovación, se oficializó el 8 de diciembre de 2006, y consiste de un conjunto de acciones institucionales e individuales orientadas a promover y facilitar el desarrollo, la asimilación y
Revista Entre Ciencia e Ingeniería
doaj +2 more sources
Entre Ciencia e Ingeniería, 2014 Breve resumen de los contenidos científicos que hay en la revistas de El Salvador Ciencia y ...
revista Entre ciencia e ingeniería
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Revista de Metalurgia, 2007 En este trabajo se ha evaluado el comportamiento a desgaste de recubrimientos de material compuesto reforzado con un 20 % de partículas de SiC fabricados por proyección térmica con llama oxiacetilénica.
M. Campo +4 more
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Institucionalidad de innovación, ciencia y tecnología en El Salvador.
, 2013 La carpeta de propuesta de "Institucionalidad" hace un Diagnóstico de documentos como: El índice de Crecimiento de la Competitividad (ICC); "informe Global de Competitividad 2012-2013, World Economic Forum"; los principales indicadores macroeconómia del ...
Consejo Nacional de Ciencia y Tecnología (CONACYT)
core +1 more source