Results 21 to 30 of about 21,996,780 (301)
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Fortalecimiento del consejo nacional de ciencia y tecnología. [PDF]
, 2013 Breve reseña história del Consejo Nacional de Ciencia Tecnología y fortalecimientos que ha tenido desde sus inicio en 1992 hasta la ...
Consejo Nacional de Ciencia y Tecnología (CONACYT)
core
Programación Matemática y Software, 2015 Los proyectos Science Gateway han cambiado la forma de trabajo para muchas comunidades científicas y de ingeniería al permitir abordar nuevos problemas científicos con el uso de e-infraestructura.
José de Jesús Cruz Guzmán +5 more
doaj
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Entre Ciencia e Ingeniería, 2012 Editorial de la Revista Entre Ciencia e Ingeniería No ...
Revista Entre ciencia e ingeniería
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu +110 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada +7 more
wiley +1 more source
Institucionalidad de la Ciencia, Tecnología e Innovación en Colombia [PDF]
Documento que expone las condiciones para que el conocimiento sea un instrumento de desarrollo, atendiendo los siguientes desafíos: 1. Acelerar el crecimiento económico 2. Disminuir la inequidad 3.
Departamento Administrativo de Ciencia, Tecnología e Innovación - Colciencias
core +2 more sources