Results 61 to 70 of about 99,752 (255)

KRT14 Drives Basal Muscle‐Invasive Bladder Cancer Progression and Lung Metastasis by Directly Binding to and Stabilizing IGF2BP1

open access: yesAdvanced Science, EarlyView.
We identified a Krt14+ Igf2bp1+ bladder cancer population linked to EMT. Mechanistically, KRT14 stabilizes and transports IGF2BP1 to invasive protrusions, initiating a positive feedback loop that drives metastasis and poor outcomes. ABSTRACT Basal‐type muscle‐invasive bladder cancer (BMIBC) is characterized by aggressive metastasis and poor prognosis ...
Shirui Huang   +19 more
wiley   +1 more source

Regulation of e-cigarettes

open access: yesAsian Medical Journal and Alternative Medicine, 2019
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openaire   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

open access: yesAdvanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu   +12 more
wiley   +1 more source

The prevalence and predictors of vaping quit attempt among electronic cigarette users: findings from provincial version of Global Adult Tobacco Survey 2020 in Vietnam

open access: yesBMC Public Health
Background Electronic cigarette (e-cigarette) quit attempts among users have been a topic of increasing focus in high-income countries, but limited research exists in low- and middle-income countries (LMICs).
Thi Phuong Thao Tran   +9 more
doaj   +1 more source

Perception of the relative harm of electronic cigarettes compared to cigarettes amongst US adults from 2013 to 2016: analysis of the Population Assessment of Tobacco and Health (PATH) study data

open access: yesHarm Reduction Journal, 2020
Background Electronic cigarettes (e-cigarettes) have been characterised as significantly less harmful than cigarettes by many health agencies and regulators globally.
Layla Malt   +6 more
doaj   +1 more source

Per‐ and Polyfluoroalkyl Substances (PFAS) Exposure Profiles and Their Predictors in a Study of US Volunteer Firefighters

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Introduction Firefighters may experience occupational exposure to per‐ and polyfluoroalkyl substances (PFAS). Volunteer firefighters make up 65% of the US fire service, but their serum PFAS profiles have not been well characterized. This study aims to (1) describe PFAS serum profiles among US volunteer firefighters from 9 states enrolled in ...
Katherine A. Lubina   +16 more
wiley   +1 more source

E-cigarette use, perceived risks, attitudes, opinions of e-cigarette policies, and associated factors among Thai university students

open access: yesTobacco Induced Diseases
Introduction Although many countries, including Thailand, currently ban the sale of e-cigarettes, their use continues to rise, especially among young adults.
Tippanart Vichayanrat   +5 more
doaj   +1 more source

Assessment of Genetic Correlations Between Tobacco or Alcohol Use and Neurodegenerative Diseases Using East Asian Genetic Ancestry Genome‐Wide Association Study Results

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Alzheimer's disease (AD) and Parkinson's disease (PD) are the most prevalent late‐onset neurodegenerative diseases worldwide. Both are influenced in part by genetic factors and are currently incurable. Tobacco and alcohol, the two most common substances used among the general adult population, are potential AD/PD risk factors and are also ...
Linda Wang   +3 more
wiley   +1 more source

A look at market and patterns of the use of electronic cigarettes in Poland: current and future risks for tobacco control

open access: yesTobacco Prevention and Cessation, 2019
In the past 10 years, a sharp increase in sale of e-cigarettes is observed on Polish tobacco market. Between 2008 and 2011, when sale of e-cigarettes reached a peak, the market expanded almost 8 times.
Krzysztof Przewoźniak
doaj   +1 more source

Measuring Child Disadvantage: Comparing Multidimensional and Socioeconomic Approaches for Predicting Developmental Outcomes

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Robust measurement of disadvantage is essential to identifying and addressing inequities in children's development. We tested how a multidimensional framework of child disadvantage performed relative to a traditional socioeconomic position (SEP) approach to predict developmental outcomes.
Wei Hong   +7 more
wiley   +1 more source

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