Results 41 to 50 of about 22,904 (279)

Designing Open Educational Resources through Knowledge Maps to enhance Meaningful learning [PDF]

, 2008
This paper demonstrates some pedagogical strategies for developing Open Educational Resources (OERs) using the knowledge mapping tool Compendium. It also describes applications of Knowledge Maps to facilitate meaningful learning by focusing on specific ...
Connolly, Teresa, Okada, Alexandra
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Challenges in the delivery of e-government through kiosks [PDF]

, 2004
Kiosks are increasingly being heralded as a technology through which governments, government departments and local authorities or municipalities can engage with citizens.
A. Evangelidis, A. Macintosh, A. Watson, A.B. Lindberg, B. Gunter, D. Gouscos, D. Nicholas, I. Chisholm, J. Inman, J. Kraaijenbrink, J. Munro, L.F. Cranor, L.L. Tung, OECD, P. Morath, P. Williams, R. Ashford, R. Leenes, V. Jacumeit, X. Chen   +19 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

La democràcia electrònica, de Jordi Sànchez i Picanyol

IDP, 2006
El primer número de la col·lecció "Vull Saber", titulat La democràcia electrònica i escrit pel politòleg Jordi Sànchez, és molt pertinent perquè el tema és de gran actualitat i pot interessar tant a polítics i autoritats com a qualsevol ciutadà que faci ...
Rosa Borge
doaj   +1 more source

The effect of new technologies on civic participation models [PDF]

, 2018
The development of new technologies will enable decentralization and freedom of communication for large numbers of people, by overcoming the barriers that once rendered direct participation of society unfeasible.
Holubiak, Nataliia
core   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Comprendre le territoire de Venise

Netcom, 2010
The research project PANDORA - PArticipatory Networks and Databases fOr sustainable Research and Assessment (www.feempandora.it) – of Enrico Mattei Eni Foundation started an Action Research analysis aiming at experimenting innovative forms of ...
Lorena Rocca
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Dilema E-Democracy di Indonesia: Menganalisis Relasi Internet, Negara, dan Masyarakat

Jurnal Komunikasi, 2016
Implementation of e-democracy in Indonesia is still problematic. This notions based on three arguments which is discussed in this article. First, e-democracy is just the facilities or the goals?
Ahmad Alwajih
doaj