Results 131 to 140 of about 23,390,793 (329)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
HeliyonThe widespread adoption of electronic devices has enhanced living standards but has also led to a surge in electronic waste (e-waste), creating serious environmental and health challenges.
Kaniz Fatema +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Why should support schemes for renewable electricity complement the EU emissions trading scheme? [PDF]
In virtually all EU Member States, the EU Emissions Trading Scheme (EU ETS) is complemented by support schemes for electricity generation from renewable energy sources (RES-E). This policy mix has been subject to strong criticism.
Gawel, Erik, Lehmann, Paul
core
HeliyonThe soaring rise of electronic and electrical waste (E-waste) leads to significant challenges to the South Asian region, urging for incorporating comprehensive assessment and management strategies.
Md. Kaviul Islam +2 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Wind power integration, negative prices and power system flexibility - An empirical analysis of extreme events in Germany [PDF]
This article analyses the flexibility of the German power market with respect to the integration of an increasing share of electricity from renewable energy sources.
Nicolosi, S.
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
European Papers(Series Information) European Papers - A Journal on Law and Integration, 2024 9(3), 1148-1179 | Article | (Table of Contents) I. Introduction. – II. The use of conditionality instruments in EU law – III. Varieties of conditionality instruments. – IV. The
Cristina Fasone, Marta Simoncini
doaj +1 more source