Results 141 to 150 of about 23,390,793 (329)
Next-generation genotype imputation service and methods
Nature Genetics, 2016 Sayantani Das, L. Forer, S. Schönherr, C. Sidore, A. Locke, Alan M. Kwong, S. Vrieze, E. Chew, S. Levy, M. McGue, D. Schlessinger, D. Stambolian, Po-Ru Loh, W. Iacono, A. Swaroop, L. Scott, F. Cucca, F. Kronenberg, M. Boehnke, G. Abecasis, C. Fuchsberger +20 moresemanticscholar +1 more sourceNext-generation characterization of the Cancer Cell Line Encyclopedia
Nature, 2019 M. Ghandi, F. Huang, Judit Jané-Valbuena, G. Kryukov, Christopher C. Lo, E. McDonald, J. Barretina, Ellen T. Gelfand, C. Bielski, Haoxin Li, K. Hu, Alexander Y. Andreev-Drakhlin, Jaegil Kim, J. Hess, B. Haas, F. Aguet, B. Weir, M. Rothberg, B. Paolella, M. Lawrence, Rehan Akbani, Yiling Lu, Hong L. Tiv, P. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, J. Shih, Kevin Hadi, Yanay Rosen, J. Bistline, K. Venkatesan, Anupama Reddy, D. Sonkin, Manway Liu, J. Lehár, Joshua M. Korn, D. Porter, Michael D. Jones, J. Golji, G. Caponigro, Jordan E. Taylor, C. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, A. Kauffmann, Nicolas Stransky, M. Imieliński, Y. Maruvka, A. Cherniack, Aviad Tsherniak, F. Vazquez, Jacob D. Jaffe, A. Lane, D. Weinstock, Cory M. Johannessen, Michael P. Morrissey, F. Stegmeier, R. Schlegel, W. Hahn, G. Getz, G. Mills, J. Boehm, T. Golub, L. Garraway, W. Sellers +67 moresemanticscholar +1 more sourceMultiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst +6 morewiley +1 more sourceScenarios for an Energy Policy Concept of the German Government [PDF]
In this working paper we demonstrate how challenging greenhouse gas reduction targets of up to 95% until 2050 can be achieved in the German electricity sector. In the analysis, we focus on the main requirements to reach such challenging targets.Fürsch, Michaela, Lindenberger, Dietmar, Nagl, Stephan, Paulus, Moritz, Richter, Jan, Trueby, Johannes +5 morecore A second generation human haplotype map of over 3.1 million SNPs
Nature, 2007 K. Frazer, D. Ballinger, D. Cox, D. Hinds, L. Stuve, R. Gibbs, J. Belmont, A. Boudreau, P. Hardenbol, S. Leal, S. Pasternak, D. Wheeler, T. Willis, F. Yu, Huanming Yang, Changqing Zeng, Yang Gao, Haoran Hu, Weitao Hu, Chaohua Li, Wei Lin, Siqi Liu, Hao Pan, Xiaoli Tang, Jian Wang, Wei Wang, Jun Yu, Bo Zhang, Qingrun Zhang, Hongbin Zhao, Hui-Ping Zhao, Jun Zhou, S. Gabriel, Rachel Barry, B. Blumenstiel, Amy L. Camargo, M. DeFelice, M. Faggart, Marie-Anne Goyette, Supriya Gupta, Jamie M Moore, Huy L. Nguyen, R. Onofrio, Melissa Parkin, J. Roy, E. Stahl, E. Winchester, L. Ziaugra, D. Altshuler, Yan Shen, Zhijian Yao, Wei Huang, X. Chu, Yungang He, Li Jin, Yangfan Liu, Yayun Shen, Weiwei Sun, Haifeng Wang, Yi Wang, Ying Wang, Xiao-yan Xiong, Liang Xu, M. Waye, S. Tsui, H. Xue, J. Wong, L. Galver, Jian-Bing Fan, K. Gunderson, S. Murray, A. Oliphant, M. Chee, A. Montpetit, F. Chagnon, Vincent Ferretti, M. Leboeuf, J. Olivier, M. Phillips, Stéphanie Roumy, C. Sallée, A. Verner, T. Hudson, P. Kwok, Dongmei Cai, D. Koboldt, Raymond D. Miller, L. Pawlikowska, P. Taillon-Miller, M. Xiao, L. Tsui, W. Mak, You-Qiang Song, P. Tam, Yusuke Nakamura, T. Kawaguchi, T. Kitamoto, Takashi Morizono, A. Nagashima, Y. Ohnishi, A. Sekine, Toshihiro Tanaka, T. Tsunoda, P. Deloukas, C. Bird, Marcos Delgado, E. Dermitzakis, R. Gwilliam, S. Hunt, J. Morrison, Don Powell, B. Stranger, P. Whittaker, D. Bentley, M. Daly, P. D. de Bakker, J. Barrett, Y. Chretien, J. Maller, S. Mccarroll, N. Patterson, I. Pe’er, A. Price, S. Purcell, D. Richter, Pardis C Sabeti, R. Saxena, S. Schaffner, P. Sham, P. Varilly, Lincoln D. Stein, Lalitha Krishnan, A. Smith, M. Tello-Ruiz, Gudmundur A. Thorisson, A. Chakravarti, Peter E. Chen, D. Cutler, C. Kashuk, Shin Lin, G. Abecasis, W. Guan, Yun Li, Heather M. Munro, Zhaohui S. Qin, D. Thomas, G. McVean, A. Auton, L. Bottolo, Niall J. Cardin, S. Eyheramendy, C. Freeman, J. Marchini, S. Myers, C. Spencer, M. Stephens, P. Donnelly, L. Cardon, G. Clarke, David M. Evans, A. Morris, B. Weir, J. Mullikin, S. Sherry, M. Feolo, Andrew Skol, Houcan Zhang, I. Matsuda, Y. Fukushima, D. Macer, Eiko Suda, C. Rotimi, C. Adebamowo, I. Ajayi, Toyin I G Aniagwu, P. Marshall, C. Nkwodimmah, C. Royal, M. Leppert, M. Dixon, A. Peiffer, Renzong Qiu, A. Kent, Kazuto Kato, N. Niikawa, I. Adewole, B. Knoppers, Morris W. Foster, E. Clayton, Jessica Watkin, D. Muzny, L. Nazareth, E. Sodergren, G. Weinstock, I. Yakub, B. Birren, R. Wilson, L. Fulton, J. Rogers, J. Burton, N. Carter, C. Clee, M. Griffiths, Matthew C. Jones, K. McLay, R. Plumb, M. Ross, S. Sims, D. Willey, Zhu Chen, Hua Han, L. Kang, M. Godbout, J. Wallenburg, P. L'Archevêque, G. Bellemare, Koji Saeki, Hongguang Wang, Daochang An, Hongbo Fu, Qing Li, Zhen Wang, Ren-hao Wang, A. Holden, L. Brooks, J. Mcewen, M. Guyer, V. Wang, Jane L. Peterson, Michael Shi, J. Spiegel, L. M. Sung, Lynn F. Zacharia, F. Collins, Karen L Kennedy, Ruth Jamieson, J. Stewart +236 moresemanticscholar +1 more sourceThe newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...Dylan Casey, Zeqian Gao, Joan Boyeswiley +1 more source
