Results 151 to 160 of about 31,819,981 (309)

E-governance at the Local Government Level in the Philippines: An Assessment of City Government Websites [PDF]

The application of information and communication technology for improving governance by enhancing government's role in service delivery, public administration, and promotion of participatory democracy has been gaining momentum in many parts of the world.
Siar, Sheila V.
core   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

E-government and E-governance : Local Implementation of E-government Polices in Sweden

, 2014
QC ...
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Continual innovation e-governance through information technology and knowledge management

, 2006
Web and Information technologies have brought with themselves a revolution of change in sociopolitical and economic interdependencies of different countries.
Godara, Varuna
core  

Securing e-governance against shadow attacks with blockchain technology. [PDF]

Sci Rep
Mishra P, R G.
europepmc   +1 more source

EFFECT OF E-GOVERNANCE POLICY ON SECURITY IN NIGERIA

Malete Journal of Accounting and Finance
Security is a fundamental pillar for the stability and development of societies worldwide. EGovernance policy, which involves the use of digital tools and technologies in government operations, has emerged as a critical strategy for addressing modern ...
Bashi B Musa, Abu Idris, Yusuf Abdulhakeem, Ndagi Salihu   +3 more
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Vision transformer-powered conversational agent for real-time Indian Sign Language e-governance accessibility. [PDF]

Sci Rep
Nedungadi P, Dileep G, Geetha M, Raman R.   +3 more
europepmc   +1 more source