Results 181 to 190 of about 96,753 (265)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Artificial Intelligence Legal Literacy and Procedure-Concordant Use of an AI-Enabled Early-Warning System Among Hospital Nurses in Romania. [PDF]

Nurs Rep
Tănase AD, Mureșan CO, Dinu Ș, Pădure A, Ille CE, Niculescu CIT.   +5 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Community Perspectives on Effectiveness of Forest Governance and Conservation Behavior in Southwest Ethiopia: A Structural Equation Modelling and Qualitative Insights Approach. [PDF]

Environ Manage
Jebessa GM, Bekele AE, Tolera T.
europepmc   +1 more source

Potential of different area-based governance mechanisms for achieving Global Biodiversity Framework goals. [PDF]

Nat Commun
Negret PJ, Rincon-Parra VJ, Jones KR, Rathbone VR, Novoa S, Quispe M, Valdés-Velásquez A, Forero-Medina G, Schleicher J, Amano T, Saravia M, Zaehringer JG.   +11 more
europepmc   +1 more source

Toward fairness in digital consumer protection: a comparative legal and socio-regulatory perspective on digital platform governance. [PDF]

Front Sociol
Akkhateerathitiphum R.
europepmc   +1 more source