Results 161 to 170 of about 34,125,650 (293)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Northern Territory Government gazette : no. G16

open access: yes, 1993
Made available via the Publications (Legal Deposit) Act 2004 (NT).This publication contains many links to external sites.

core  

Factors influencing the adoption of e-government by female university students. [PDF]

open access: yesPLoS One
Rodríguez-Correa PA   +7 more
europepmc   +1 more source

Characterization of e-Government adoption in Europe. [PDF]

open access: yesPLoS One, 2020
Yera A   +3 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Northern Territory Government gazette : no. G16

open access: yes, 2001
Made available via the Publications (Legal Deposit) Act 2004 (NT).This publication contains may contain links to external sites.

core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Northern Territory Government gazette : no. G7

open access: yes, 2009
Made available via the Publications (Legal Deposit) Act 2004 (NT).This publication contains may contain links to external sites.

core  

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