Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
E-Health and M-Health in Obesity Management: A Systematic Review and Meta-Analysis of RCTs. [PDF]
Chiavarini M +3 more
europepmc +1 more source
Examining the relationships between e-health literacy, cyberchondria, health anxiety, and health perception among foreign university students. [PDF]
Aslan H, Koca GŞ.
europepmc +1 more source
Bridging the digital divide: A snapshot on e-health literacy among medical students in Tamil Nadu, South India. [PDF]
Kulothungan K +9 more
europepmc +1 more source
An Analysis of Switching Behavior from Traditional Hospital Visit to E-Health Consultation. [PDF]
Sriram S +3 more
europepmc +1 more source
A ZKP-based anonymous biometric authentication scheme for the E-health systems. [PDF]
Mao X, Zhou X, Zhao X, Chen Y.
europepmc +1 more source

