Results 41 to 50 of about 98,090 (266)

In Search of Smartness: The EU e-Justice Challenge [PDF]

Informatics, 2017
At the EU level, an increasing number of resources are being invested in an attempt to provide better public services through the use of Information and Communication Technology (ICT). While new tools are being designed and implemented, a shift from ‘traditional’ technologies that must be used to provide services to more interactive ‘smart ...
openaire   +4 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

e-Justice in France: the e-Barreau experience

Utrecht Law Review, 2011
Recent field research projects in the justice sector have shown how the development of e-justice entails much more than developing, installing and connecting technological devices or providing normative recognition to the use of the digital medium ...
Marco Velicogna, Antoine Errera, Stéphane Derlange   +2 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The Impact of Digitalization on Sustainable Development Indicators [PDF]

Revista de Studii Financiare
One of the major objectives of the EU is digitalization. The impact of digitalization is different from one sector to another and sometimes in contradiction with sustainability.
Silviu Cârstina, Mirela Cristea, Marian Ilie Siminică, Daniel Cîrciumaru, Gabriela Badareu   +4 more
doaj   +1 more source

Hospitalization following eating disorder diagnosis: The buffering effect of marriage and childbearing events

SSM: Population Health, 2020
Eating Disorders (ED) are defined as abnormal eating behaviors, stemming from an obsession with food, body weight, or body shape. EDs affect 10 million men and 20 million women in the US, with an estimated 15% lifetime prevalence among women.
Jennifer Tabler, Rebecca L. Utz
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Risk factors in e-justice information systems

Government Information Quarterly, 2013
AbstractWith the increase of the communication systems' bandwidth and with the dissemination of the information systems, the fields of information and communication technology application expanded in almost all directions. E-government in general and e-justice in particular are no exception and these areas suffered strong changes in the last decades ...
João Rosa, Claudio Teixeira, Joaquim Sousa Pinto   +2 more
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source