Results 61 to 70 of about 98,090 (266)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

The Effects of Perceived Justice and Emotions on Service Recovery Satisfaction on Indonesian Ecommerce Customers

Jurnal Sistem Informasi, 2020
This study aims to analyze the effects of justice theory and emotions on service recovery satisfaction of Indonesian e-commerce customers. The factors used in this study are distributive justice, procedural justice, interactional justice, as cognitive ...
Fatimah Azzahro, Putu Wuri Handayani, Sandya Sekar Murti, Satrio Baskoro Yudhoatmojo   +3 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Legal Characteristics of Electronic Justice as Project of Electronic Democracy in the Context of the International Practice and Influence of Electronic Justice on Ensuring Independence and Impartiality of Bodies of Judicial Authority

Управленческое консультирование, 2018
There are various forms and legal mechanisms for e-democracy. It includes an e-justice. E-justice is characterized by transparency, accountability, transparency of information, provision of electronic document.
Yaroslav Valeryevich Antonov
doaj  

THE INFLUENCE OF PUBLIC POLICIES FOR DEVELOPMENT OF ST&I IN BRAZIL: THE ANALYSIS OF THE SNCTI INDICATORS

Revista Brasileira de Gestão e Inovação, 2023
The National System of Science, Technology and Innovation (SNCTI) in Brazil comprises an environment formed by public and private institutions, funding agencies, research companies, in addition to a number of instruments instituted in favor of the ...
Ana Cristina dos Santos, Ana Cristina de Lima Cardoso Carvalho, Paulo Eduardo Mascarello Gobbi, Paula Meyer Soares, Leila Maria da Juda Bijos   +4 more
doaj  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

e-Justice Governance in the EU

Technology use has been seen as a way to make access to justice easier, faster, and more efficient. In the EU, e-justice actions have been centred around supporting activities leading to building up access to legal information, access to courts and extrajudicial procedures in a cross-border setting, and communication between judicial authorities. These
openaire   +2 more sources