Results 71 to 80 of about 98,461 (311)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

International experience of implementing e-justice: best practices and challenges

open access: yesТеорія і практика правознавства
The implementation of e-justice is an important aspect of the modernization of judicial systems around the world. Research and analysis of international experience allows to identify best practices and challenges faced by other countries during the ...
Kristina Piatyhora
doaj   +1 more source

A non-ideal global basic structure

open access: yesEtikk i Praksis: Nordic Journal of Applied Ethics, 2016
Focusing on the basic structure as the subject of justice has tended to lead theorists to make a choice: either there is no global basic structure and therefore obligations of justice remain domestic only (the statist position) or there is sufficient ...
Sabrina Martin
doaj   +1 more source

Justice online: a new kind of justice? [PDF]

open access: yes, 2012
It is a fact that mediation and other alternative dispute resolution means are becoming increasingly popular. Actually, governments are encouraging people to use them instead of going to Court, as they are quicker, cheaper and more informal than trials ...
Calheiros, Clara
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Undergraduate Commencement Exercises Program, May 18, 1991. [PDF]

open access: yes, 1991
Bryant University Undergraduate Commencement Exercises Program, May 18 ...

core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

THE INFLUENCE OF PUBLIC POLICIES FOR DEVELOPMENT OF ST&I IN BRAZIL: THE ANALYSIS OF THE SNCTI INDICATORS

open access: yesRevista Brasileira de Gestão e Inovação, 2023
The National System of Science, Technology and Innovation (SNCTI) in Brazil comprises an environment formed by public and private institutions, funding agencies, research companies, in addition to a number of instruments instituted in favor of the ...
Ana Cristina dos Santos   +4 more
doaj  

Spartan Daily, January 12, 1954 [PDF]

open access: yes, 1954
Volume 42, Issue 62https://scholarworks.sjsu.edu/spartandaily/11958/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +1 more source

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