Results 181 to 190 of about 32,759,036 (278)

Publishing the History of Radical Science in a Time of Digital Capitalism

Berichte zur Wissenschaftsgeschichte, EarlyView.
This paper investigates publishing as a practice in the history of science. It firstly provides an experiential account of building a DIY‐inspired publishing venue for collective, source‐based narration. The venue used the possibilities of digital publishing to apply, rather than simply refer to, a very striking aspect of radical science in the 1970s ...
Niki Rhyner
wiley   +1 more source

Multi-Target Virtual Screening of Natural Products Against Virulence-Associated Proteins of <i>Pseudomonas aeruginosa</i> PAO1 for Antivirulence Candidate Prioritization. [PDF]

Pharmaceuticals (Basel)
Chen W, Zhang Y, Zeng J, Wang Y, Cheng B.   +4 more
europepmc   +1 more source

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

Biotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga, Udisha Singh, Sachin Dattram Pawar   +2 more
wiley   +1 more source

Association of gestational diabetes with other lactation-related disorders: A 2-sample Mendelian randomization analysis of causal effects. [PDF]

Medicine (Baltimore)
Yang C, Song W, Lu K, Dang W, Li J, Wang Y, Zhang M, Cheng X, Wu X.   +8 more
europepmc   +1 more source

Induction Temperature and Feeding Profile Shape the Partitioning Between Soluble Product and Inclusion Body Formation in Escherichia coli

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Inclusion body (IB) processes yielding the recombinant product only as IBs are long‐established in the biopharmaceutical industry. Yet, for recombinant proteins that accumulate both IBs and soluble fraction depending on the selected upstream processing (USP) strategy, the influence of process parameters on the partitioning between both forms ...
Mohamed Elshazly, Lisa Ying, Florian Gisperg, Robert Klausser, Eva Prada Brichtova, Noah Schütz, Oliver Spadiut, Julian Kopp   +7 more
wiley   +1 more source

Multilevel genomic, transcriptomic, and epidemiologic evidence linking diabetic retinopathy to Alzheimer disease. [PDF]

J Glob Health
Li J, Liu Q, Ma Q, Shen T, Xia J, Yang X, Liu K, Li N, Yan B.   +8 more
europepmc   +1 more source

Cultivating Collaboration in BioMolViz: Key Attributes for Building a STEM Educator Community of Practice

Biochemistry and Molecular Biology Education, EarlyView.
ABSTRACT BioMolViz is an educational community of practice (CoP) focused on creating resources to improve biomolecular visual literacy instruction and assessment. The community of life science instructors developed in three phases, beginning with a small Core Team that emerged from a conference session and established the domain of interest for the CoP.
Pamela S. Mertz, Charmita Burch, Roderico Acevedo, Josh T. Beckham, Didem Vardar‐Ulu, Kristin M. Fox, Lauren A. Genova, Rachel M. Mitton‐Fry, Swati Agrawal, Daniel R. Dries, Kristen Procko   +10 more
wiley   +1 more source

Genetic liability to ADHD and migraine risk: Mendelian randomization evidence for behavioural and psychiatric pathways

Luo Y, Dardani C, Wootton RE, Sanderson ECM, Stergiakouli E.   +4 more
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Dual‐targeted nanomedicine delivering doxorubicin and nitric oxide for tumor immunomodulation and synergistic therapy

BMEMat, EarlyView.
The mechanism of HA‐DS@PLGA nanoparticles co‐delivering DOX and SNAP (an NO donor) to suppress tumor growth, remodel the tumor microenvironment, and enhance antitumor immune responses for effective combinatorial cancer therapy. Abstract Cancer therapeutic efficacy is significantly influenced by tumor immunosuppressive environment possibly induced by ...
Xingzhou Peng, Wei Chen, Shuyu Li, Xiaomin Ma, Yanfeng Dai, Yan Wang, Changqiang Xie, Yazhe Xiao, Hesong Han, Yumiao Zhang, Junjie Wang   +10 more
wiley   +1 more source