Results 141 to 150 of about 23,402,107 (303)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Essential components of e-maintenance

open access: yes, 2011
Validerad; 2011; 20110413 (raka)
Kajko-Mattsson, Mira   +2 more
openaire   +1 more source

The Management of the Industrial Maintenance at an International Level (II) [PDF]

open access: yes
When defining a maintenance policy, it must be held in mind the fact that there isn’t such a thing like “good maintenance policy” in itself; instead, for each industrial equipment should be adapted a particular maintenance method, coming to a technical ...
Florea PARVU   +3 more
core  

Fatores de início e manutenção da obesidade/excesso de peso: uma comparação entre adultos com binge eating e sem binge eating

open access: yesRevista Brasileira de Obesidade, Nutrição e Emagrecimento, 2018
O sobrepeso e a obesidade são atualmente um problema grave de saúde pública. Neste sentido foram objetivos deste estudo explorar os fatores e processos associados ao início do excesso de peso e à manutenção de obesidade/excesso de peso e perceber se ...
Cristina Martins Horta   +3 more
doaj  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

E-Maintenance : Opportunities and Challenges

open access: yes, 2011
ReDi2Service
Chowdhury, Soumitra, Akram, Asif
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Maintenance Strategies to Reduce Downtime Due to Machine Positional Errors

open access: yes, 2014
Manufacturing strives to reduce waste and increase Overall Equipment Effectiveness (OEE). When managing machine tool maintenance a manufacturer must apply an appropriate decision technique in order to reveal hidden costs associated with production ...
Longstaff, Andrew P.   +5 more
core   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

A value-centric decision making framework for maintenance services outsourcing [PDF]

open access: yes, 2011
The shift in mindset of decision makers, from maintenance being a “necessary evil” and “cost centre” to a “profit contributor” in manufacturing companies has driven outsourced maintenance suppliers to employ value-centric approaches in order to design
Toossi, Amir
core  

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