Results 141 to 150 of about 23,402,107 (303)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Essential components of e-maintenance
Validerad; 2011; 20110413 (raka)
Kajko-Mattsson, Mira +2 more
openaire +1 more source
The Management of the Industrial Maintenance at an International Level (II) [PDF]
When defining a maintenance policy, it must be held in mind the fact that there isn’t such a thing like “good maintenance policy” in itself; instead, for each industrial equipment should be adapted a particular maintenance method, coming to a technical ...
Florea PARVU +3 more
core
O sobrepeso e a obesidade são atualmente um problema grave de saúde pública. Neste sentido foram objetivos deste estudo explorar os fatores e processos associados ao início do excesso de peso e à manutenção de obesidade/excesso de peso e perceber se ...
Cristina Martins Horta +3 more
doaj
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
E-Maintenance : Opportunities and Challenges
ReDi2Service
Chowdhury, Soumitra, Akram, Asif
openaire +2 more sources
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Maintenance Strategies to Reduce Downtime Due to Machine Positional Errors
Manufacturing strives to reduce waste and increase Overall Equipment Effectiveness (OEE). When managing machine tool maintenance a manufacturer must apply an appropriate decision technique in order to reveal hidden costs associated with production ...
Longstaff, Andrew P. +5 more
core +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
A value-centric decision making framework for maintenance services outsourcing [PDF]
The shift in mindset of decision makers, from maintenance being a “necessary evil” and “cost centre” to a “profit contributor” in manufacturing companies has driven outsourced maintenance suppliers to employ value-centric approaches in order to design
Toossi, Amir
core

