Results 41 to 50 of about 35,070,485 (279)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Development of e-Navigation [PDF]
TransNav, 2007 E-navigation is, at the moment, a catchall phrase for a concept of bringing existing and new technology together to improve safety of navigation, commercial efficiency and security.
David Patraiko
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
The role of integrity for maritime traffic situation assessment [PDF]
, 2011 Starting from the E-Navigation concept of IMO this paper will give an overview about integrity in maritime traffic awareness. Derived from a DLR study a concept is presented which introduces the provision of integrity maritime traffic awareness.
Engler, Evelin +3 more
core
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Congested Area Detection and Projection - the User's Requirements [PDF]
TransNav, 2011 Shanghai Maritime University and Gdynia Maritime University have decided to join forces on research program titled ?Online detecting and publishing of congested zones at sea?.
Tadeusz Stupak, Stanislaw Zurkiewicz
doaj
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Dimensi Metrik Graf Kr+mKsr, m, r, s, En
Cauchy: Jurnal Matematika Murni dan Aplikasi, 2011 The concept of minimum resolving set has proved to be useful and or related to a variety of fields such as Chemistry, Robotic Navigation, and Combinatorial Search and Optimization. So that, this thesis explains the metric dimension of graph Kr + mKsr, m,
Hindayani Hindayani
doaj +1 more source