Results 131 to 140 of about 33,407,304 (291)

Centralization of the System of E-Participation in the Russian Federation: Expert Interviews Data

open access: yesУправленческое консультирование
This article presents the results of the study aimed at analyzing the institutional transformations of the E-Participation system in Russia. Since 2020, the e-participation system in Russia has undergone significant transformations associated with the ...
G. O. Panfilov, A. V. Chugunov
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Dimensions of e-Participation

open access: yesProceedings of the 15th International Conference on Theory and Practice of Electronic Governance, 2022
Leif Sundberg, Katarina Gidlund
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

National communication strategies of the European Union: the experience of the Netherlands

open access: yesStudia Humanitatis, 2015
On the basis of analysis of faults and achievements in communication with EU citizens and in order to overcome the "communication gap" the European Union elaborated its own communication policy where are stipulated its principles and directions of ...
Karpchuk Natalia Petrivna
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Political participation in Jordan: the impact of party and tribal loyalties since 1989 [PDF]

open access: yes, 2008
In the light of the internal and regional crises in the 1980s, Jordan found itself under pressure, and various ideological and political factors pushed the country towards political reform. As a result, Jordan has undergone several transformations, and a
Alazzam, Amin Ali
core  

Evaluating the Efficacy of E-Participation Experiences

open access: yes, 2013
In the last decade, a number of e-participation experiences have been collected based on the use of information and communication technologies (ICT). These projects have made a contribution to the revitalisation of democracy by increasing transparency in
Wimmer, Maria A.   +2 more
core   +1 more source

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