Results 151 to 160 of about 23,307,222 (310)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Participation Outcomes In Rehabilitation For Individuals With Chronic Neurological Conditions

open access: yes, 2018
The purpose of this research project was to identify personal and environmental factors that facilitate both ability to participate in life roles and satisfaction with that participation, for people living with chronic neurological conditions ...
Dobler, Sherry
core  

المشاركة الإلكترونية – نحو مفهوم يتجاوز التغريد-

open access: yesمجلة الآداب و العلوم الإجتماعية, 2018
تسعى الورقة البحثية إلى مناقشة مدى مساهمة أدوات المشاركة القائمة على تكنولوجيا المعلومات والاتصالات بشكل مباشر في تحقيق نتائج المشاركة الإلكترونية. مفترضة بأن توفير المعلومات وتيسير الإجراءات تعزز قدرة وفعالية المواطنين في المشاركة في تسيير الشأن العام ...
يوسف زدام
doaj  

Dimensions of e-Participation

open access: yesProceedings of the 15th International Conference on Theory and Practice of Electronic Governance, 2022
Leif Sundberg, Katarina Gidlund
openaire   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Applying an Ethical Perspective on Stakeholder Participation in Public E-service Development

open access: yes, 2013
In order to balance between citizen and agency aspects’ importance and visibility in public e-service development, the question how to involve different stakeholders is often raised. However, identifying and analyzing several internal as well as external
Axelsson, Karin
core  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

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