The Role of Pseudonymity in Mobile e-Participation [PDF]
Proceedings of the Annual Hawaii International Conference on System Sciences, 2019 Sarah-Kristin Thiel, Ida Larsen-Ledet
openaire +2 more sources
Electronic governance, premise for implementation of electronic democracy [PDF]
Living in a rapidly changing society, where information travels with great speed and its upgrade is essential, we decided to approach certain aspects of e-democracy, as a dynamic way of citizen participation, using new Information and Communications ...
Grigorovici, Iulia, Matei, Ani
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Association of Participation in Warm-Up Exercises with Complications, Subsequent Injury Frequency, and Recovery Duration Among Athletes with a History of Injury: A Physical Activity Epidemiology Study Using Secondary Survey Data. [PDF]
Medicina (Kaunas)Park EH, Kwon D, Kwon J.
europepmc +1 more source
Gamification of E-Participation: A Literature Review [PDF]
Proceedings of the Annual Hawaii International Conference on System Sciences, 2019 Hamari Juho, Hassan Lobna
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Socio-Structural Factors as Predictors of Parents' Intentions to Enrol Their Children in Swimming Lessons. [PDF]
Health Promot J AustrHamilton K +5 more
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source