Results 121 to 130 of about 33,283,713 (295)

The Militant Image Reader

open access: yes, 2015
"The Militant Image Reader brings together eight diverse texts from theorists and artists from Europe and North America that speculate on the relationship of artistic representation and social change today." -- Publisher's ...
Salloum, Jayce   +9 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

A location-based audio book reader [PDF]

open access: yes, 2012
The ability to display text on mobile devices has been progressively improved during the last decade with the growth in use of mobile devices. Recently, the e-book reader has been incorporated into travel tourism. In this project we design, implement and
Peng, Sanhong
core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Clássicos da literatura brasileira no formato de livroclip: (re)leitura e interatividade

open access: yesTexto Livre: Linguagem e Tecnologia, 2015
RESUMO: O objetivo desta comunicação é discutir como a produção de livroclip, interface interativa proveniente da computação gráfica, pode estimular o processo de (inter)ação dos aprendizes do Ensino Médio com obras clássicas da literatura brasileira ...
Suelen Érica Costa da Silva
doaj  

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Colorado reader: Colorado fires!

open access: yes, 2003
Colorado Reader, Fire, soil & water issue. February 2003.Last year in Colorado, more than 1,400 fires burned 370,000 acres. Several years of drought made 2002 one of our state’s worst fire years.
Jorda, Carrie, author   +3 more
core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

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