Results 141 to 150 of about 714,481 (251)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Miniaturized Flexible Corrosion-Resistant Tag Antenna with Folding Arm Based on Graphene Film. [PDF]

Micromachines (Basel)
Zeng M, Zhao X, Zhou H, Li J, Song R, Zu H, He D.   +6 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Exposing potential narrative structure through user choice

, 2005
The reading of a hypertext fiction could simply be viewed as the reordering of events, reviewing and accessing fragments of a story that has already taken place. A different reader experience would come from different orderings and the effects that these
Weal, Mark J.
core  

A rapid and highly sensitive CRISPR-Cas12a ortholog-assisted assay for genotyping of myostatin knockout pigs. [PDF]

Cell Biosci
Wang Y, Yang H, Zhang W, Tao D, Shi S, Li S, Wu X, Ma Y, Ruan J, Jing L, Ma K, Li X, Han X, Xu X, Xie S.   +14 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Applications of bio-feedback to muscle models

, 2011
An EMG-driven musculoskeletal model is implemented to estimate subject-specific musculoskeletal parameters such as the optimal physiological muscle length, the tendon slack length and the maximum isometric muscle force of flexor and extensor muscle ...
Mace, B.R., Colacino, F.M., Rustighi, E.
core  

A Modular Platform for Quantitative Two-Color Bioluminescence Combining NanoLuc and Red-Shifted NanoPrism Luciferases. [PDF]

ACS Chem Biol
Porter K, Killoran M, Hurst R, Klein M, De Bakshi D, Esmatpour R, Encell LP, Gama-Franceschi F, Bessetti J, Riching KM, Machleidt T, Mezzanotte L, Friedman Ohana R.   +12 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

A nordic case reader in logistics and supply chain management

, 2006
While supply chain management (SCM) and logistics are universal concepts, they are certainly not implemented the same worldwide. This case reader provides audience with a diversity of topics, industries and applications that are unique to the European ...

core