Results 91 to 100 of about 22,054,732 (308)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
, 2013 Mobile Technology (MT) provides many opportunities to individuals, such as talking with people, watching movie clips, and reading books whenever or wherever they want. This also allows individuals to frequently connect for learning.
Keskin, Nilgün Özdamar +5 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Catching Readers Before They Fall Supporting Readers Who Struggle, K-4
Every teacher of reading plays a vital role in helping to catch those readers for whom learning to read does not come easily. Through examples from both adults and children, the authors explain and describe the complex integrated network of strategies ...
Keier, Katie., Johnson, Pat.
core
The Characteristics of Adult Readers in Entry Level Tertiary Settings in New Zealand
, 2009 International literacy and life skills surveys in 1996 and 2006 assessed the broad group of skills encompassing reading, numeracy, and problem solving skills across OECD countries.
McHardy, Janet Mary
core
E-readers e cegos : uma relação difícil
, 2019 Aborda questões de acessibilidade de pessoas com deficiência visual em relação a e-readers, realiza um levantamento dos e-readers vendidos no Brasil visando identificar a existência da função texto-voz.
Viana, Santos, Vagner Almeida dos Jose Antonio Rodrigues
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Serving Teens through Readers' Advisory
Getting teens to read for fun is the ultimate challenge, yet research shows that it improves skills in grammar and spelling while expanding vocabularies.
Booth, Heather.
core
E-readers and struggling middle school readers
, 2016 Research is emerging to understand how technology affects student attitudes towards reading. Research on the influence of e-books on struggling adolescent readers, however, is limited.
Hendrickson, Abigail L.
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source