Results 111 to 120 of about 35,168,141 (194)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

E-Book Readers for Everyone: FATIH Project

open access: yes, 2013
Mobile Technology (MT) provides many opportunities to individuals, such as talking with people, watching movie clips, and reading books whenever or wherever they want. This also allows individuals to frequently connect for learning.
Keskin, Nilgün Özdamar   +6 more
core   +1 more source

Revista na versão eBook (ePub): para leitura em dispositivos móveis (e-readers, tablets, smartphones)

open access: yesTempo e Argumento, 2014
Tenha a revista completa no seu tablet, e-readers ou smartphone.
Tempo & Argumento
doaj   +2 more sources

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Serving Teens through Readers' Advisory

open access: yes
Getting teens to read for fun is the ultimate challenge, yet research shows that it improves skills in grammar and spelling while expanding vocabularies.
Booth, Heather.
core  

Turkish language teacher candidates’ thoughts on e-readers, digital reading, and reading preferences

open access: yesAnadolu Üniversitesi Eğitim Fakültesi dergisi
This research aims to determine teacher candidates’ thoughts, experiences, and expectations about digital reading and e-readers and examine students' reading habits comprehensively.
Münire Özden, Mehmet Çiçek
doaj  

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Revista na versão eBook (ePub): para leitura em dispositivos móveis (e-readers, tablets, smartphones)

open access: yes, 2012
Tenha a revista completa no seu tablet, e-readers ou ...
Tempo & Argumento   +5 more
core  

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

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