Results 111 to 120 of about 35,168,141 (194)
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
E-Book Readers for Everyone: FATIH Project
Mobile Technology (MT) provides many opportunities to individuals, such as talking with people, watching movie clips, and reading books whenever or wherever they want. This also allows individuals to frequently connect for learning.
Keskin, Nilgün Özdamar +6 more
core +1 more source
Tenha a revista completa no seu tablet, e-readers ou smartphone.
Tempo & Argumento
doaj +2 more sources
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Serving Teens through Readers' Advisory
Getting teens to read for fun is the ultimate challenge, yet research shows that it improves skills in grammar and spelling while expanding vocabularies.
Booth, Heather.
core
Turkish language teacher candidates’ thoughts on e-readers, digital reading, and reading preferences
This research aims to determine teacher candidates’ thoughts, experiences, and expectations about digital reading and e-readers and examine students' reading habits comprehensively.
Münire Özden, Mehmet Çiçek
doaj
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source

