Results 41 to 50 of about 250,781 (215)
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A project at the University of Agder has studied the use of e-readers as a tool for academic study. E-readers (Kindle DX and iPad) were loaded with texts from required reading lists in five courses with 94 participating students.
Birgitte Kleivset
doaj +1 more source
This article will examine representations and practices of digital reading among readers of novels in connection with their reading “careers.” It will draw on a qualitative study comprising thirty-six interviews with readers of novels.
Emmanuelle Guittet
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
This article will examine representations and practices of digital reading among readers of novels in connection with their reading “careers.” It will draw on a qualitative study comprising thirty-six interviews with readers of novels.
Emmanuelle Guittet
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
O USO DOS E-READERS COMO CONTRIBUIÇÃO ÀS PRÁTICAS FOCAIS: UMA ABORDAGEM FENOMENOLÓGICA
This article aims to describe and interpret the meaning of the use of e-readers in society, based on the Borgmanns phenomenology. The methodology used was a theoretical review about authors who address studies of Borgmann, technology in contemporary ...
Bruno Carvalho de Melo Rodrigues +3 more
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

