Results 121 to 130 of about 48,074,105 (310)

Building the e-science grid in the UK: middleware, applications and tools deployed at level 2 [PDF]

open access: yes, 2003
Over the period September 2002-April 2003 the UK Grid Engineering Task Force and staff at Regional e-Science Centres and CCLRC deployed the Globus Toolkit GT2 at 14 sites and on approximately 80 compute resources to set up the first production-quality e ...
Keane, Andy   +24 more
core  

Connective Ethnography for the Exploration of e-Science

open access: yesJournal of Computer-Mediated Communication, 2007
E-science comprises diverse sites, connected in complex and heterogeneous ways. While ethnography is well established as a way of exploring the detail of the knowledge production process, some strategic adaptations are prompted by this spatial complexity of e-science.
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Provenance of e-Science Experiments - experience from Bioinformatics

open access: yes, 2003
Like experiments performed at a laboratory bench, the data associated with an e-Science experiment are of reduced value if other scientists are not able to identify the origin, or provenance, of those data.
Stevens, R   +16 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 10 (1975)

open access: yes, 1975
NINETEENTH ANNUAL MEETING / April 11-12, 1975 / Joint Meeting with Arizona State University / Tempe, Arizona / Abstracts from the annual meeting of the Arizona-Nevada Academy of Science.This volume is part of the Arizona-Nevada Academy of Science ...
Arizona-Nevada Academy of Science
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Collider physics based on e-Science paradigm of experiment-computing-theory

open access: yes, 2011
Researches in the 21st century are characterized by e-Science paradigm, which is the data centric analysis as a unified concept of experiment-computing-theory. In this paper the e-Science paradigm has been realized in collider physics by constructing the
조기현, 김정현, 남수현
core  

e-Science practice and results in space science under an era of big data

open access: yes大数据, 2016
With the development of space exploration technology and the deepening of space cognition,more and more space science exploration projects have been advanced and implemented,which promoted the era of big data in space science.The foreign e-Science ...
Ziming ZOU   +4 more
doaj  

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