Results 191 to 200 of about 3,598,300 (241)

Boosting capacitive energy storage in relaxor ferroelectrics through polymorphic phase engineering. [PDF]

Sci Adv
Zhang Y, Liang H, Liu Y, Li D, Dong S, Wang J, Li W, Nan CW.   +7 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Two-dimensional NIR-II AIE nanotheranostic probes with ultralarge Stokes shifts for surgical navigation and ablation of glioma. [PDF]

Sci Adv
Liu Y, Su X, Zhong Y, Shangguan P, Zhu J, Luo Z, Wu H, Wang D, Han T, Wang J, Shi B, Tang BZ.   +11 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Community structure unveils the path multiplicity in complex networks. [PDF]

Nat Commun
Deng Y, Wu J, Lu X, Holme P, Li D, Di Z, Chen G, Kurths J.   +7 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Erratum: 2-(3-(4-Bromophenyl)-5-{3-[5-methyl-1-(4-methylphenyl)-1<i>H</i>-1,2,3-triazol-4-yl]-1-phenyl-1<i>H</i>-pyrazol-4-yl}-4,5-dihydro-1<i>H</i>-pyrazol-1-yl)-4-(4-chlorophenyl)-1,3-thiazole. Corrigendum. [PDF]

IUCrdata
El-Hiti GA, Abdel-Wahab BF, Khidre RE, Mostafa MS, Hegazy AS, Kariuki BM.   +5 more
europepmc   +1 more source

Thickness-confined metastable phase transitions drive large piezoelectricity in ultrathin BiFeO₃. [PDF]

Sci Adv
Chen SJ, Zhu M, Wang JH, Shi T, Liu J, Wang Y, Zhu Y, Ma XL, Chen Z, Tang Y.   +9 more
europepmc   +1 more source

Downregulation of Organ-Derived Activin A Attenuates Muscle Atrophy and Intramuscular Fat Infiltration in Cancer Cachexia Mice. [PDF]

J Cachexia Sarcopenia Muscle
Wang C, Gao L, Xue R, Su J, Li H, Yang W, Tang Y, Su Z, Min S, Tang C, Zhu Y, Mu B, Speakman JR, Xie X, Li Z.   +14 more
europepmc   +1 more source

Propagation of the Madden-Julian oscillation as a deterministic chaotic phenomenon. [PDF]

Sci Adv
Takasuka D, Suematsu T, Miura H, Nakano M.   +3 more
europepmc   +1 more source