Results 241 to 250 of about 48,074,105 (310)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Correction for Gao et al., Cross-linking of collagen fibrils leads to preferential gap zone mineralization in vitro. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Draft genome of <i>Escherichia coli</i> 546 with toxigenic potential, an epizootic important pathogenic isolate obtained from a sick piglet. [PDF]

Microbiol Resour Announc
Tishchenko AS, Kopyltsov SV, Sedashev AP, Machneva NL, Fedorovich SV, Elisiutikova AV.   +5 more
europepmc   +1 more source

Correction: Synthesis of heteroleptic [Sr(ddemap)(tmhd)]₂ and its use in atomic layer deposition of low carbon SrO thin films. [PDF]

RSC Adv
Lee Y, Park C, Jeong S, Lim D, Kim J, Kim H, Kim EA, Cho SY, Yoo H, Park BK, Chung TM, Lee W.   +11 more
europepmc   +1 more source

A novel adaptive quasi-Newton-type update and its global convergence without Lipschitz condition for constrained system of nonlinear monotone equations. [PDF]

PLoS One
Ahmed K, Semary HE, Al-Moisheer AS, Ibrahim SM, Halilu AS, Waziri MY, Mohamed MA, Murtala S.   +7 more
europepmc   +1 more source

Licochalcone E Ameliorates Hepatic Steatosis in Obese Mice by Activating the Sirt1/AMPK Pathway and Reducing Hepatic Lipid Accumulation. [PDF]

Biomol Ther (Seoul)
Huang WC, Wu SJ, Liu XM, Cheng SC, Lin PT, Kuo CL, Liou CJ.   +6 more
europepmc   +1 more source

A low temperature-adapted <i>Euglena gracilis</i> ecotype for outdoor biomass production in colder climates. [PDF]

Appl Environ Microbiol
Tamaki S, Ishikawa M, Nomura T, Yamada K, Suzuki K, Mochida K.   +5 more
europepmc   +1 more source