Results 231 to 240 of about 3,401,419 (278)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Ion Diffusion and (Photo)redox Conductivity in a Covalent Organic Framework. [PDF]

J Am Chem Soc
Rath BB, Lotsch BV.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Asymmetric Ketone Diene Coupling via Stereodivergent Copper Catalysis. [PDF]

J Am Chem Soc
Liu J, Zhang Z, Troya D, Chen M.
europepmc   +1 more source

Quantum chemical investigation and molecular design of coumarin-based heavy-metal-free photosensitizers for one- and two-photon excited fluorescence imaging and photodynamic therapy. [PDF]

RSC Adv
Pham TC, Tran DN, Nguyen VT, Pham VT, Tran DL, Lee S.   +5 more
europepmc   +1 more source

Conformational switching modulates excited-state pathways in a cofacial perylene dimer. [PDF]

Chem Sci
Bressan G, Hartmann D, Brouwer J, Braun EM, Bull JN, Barendt TA.   +5 more
europepmc   +1 more source

Real-Space Constrained Density Functional Theory Investigation of Site-Specific, Interfacial Charge Recombination Dynamics Across the Au Nanoparticle/TiO₂ Heterojunction. [PDF]

J Phys Chem Lett
Glenna DM, Mora Perez C, Hermosillo E, Zhao H, Qian J.   +4 more
europepmc   +1 more source

A method to study and enhance the energy efficiency of soft electrostatic actuators. [PDF]

Proc Natl Acad Sci U S A
Zhang SL, Fukushima T, Kirkman S, Koh SJA, Rothemund P, Keplinger C.   +5 more
europepmc   +1 more source