Results 91 to 100 of about 20,555,356 (408)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Localization of protein aggregation in Escherichia coli is governed by diffusion and nucleoid macromolecular crowding effect [PDF]

, 2013
Aggregates of misfolded proteins are a hallmark of many age-related diseases. Recently, they have been linked to aging of Escherichia coli (E. coli) where protein aggregates accumulate at the old pole region of the aging bacterium.
Berry, Hugues, Coquel, Anne-Sophie, Demarez, Alice, Dimiccoli, Mariella, Jacob, Jean-Pascal, Julou, Thomas, Lindner, Ariel B., Moisan, Lionel, Primet, Maël   +8 more
core   +7 more sources

Effect of phage vB_EcoM_FJ1 on the reduction of ETEC O9:H9 infection in a neonatal pig cell line

Veterinary Research, 2023
Enterotoxigenic Escherichia coli (ETEC) colonizes the intestine of young pigs causing severe diarrhoea and consequently bringing high production costs. The rise of antibiotic selective pressure together with ongoing limitations on their use, demands new ...
Alice Ferreira, Daniela Silva, Carina Almeida, Maria Elisa Rodrigues, Sónia Silva, Joana Castro, Dalila Mil-Homens, Isidro García-Meniño, Azucena Mora, Mariana Henriques, Ana Oliveira   +10 more
doaj   +1 more source

Prospective Genomic Characterization of the German Enterohemorrhagic Escherichia coli O104:H4 Outbreak by Rapid Next Generation Sequencing Technology

PLoS ONE, 2011
An ongoing outbreak of exceptionally virulent Shiga toxin (Stx)-producing Escherichia coli O104:H4 centered in Germany, has caused over 830 cases of hemolytic uremic syndrome (HUS) and 46 deaths since May 2011.
A. Mellmann, D. Harmsen, C. Cummings, Emily B. Zentz, Shana R. Leopold, A. Rico, K. Prior, R. Szczepanowski, Yongmei Ji, Wenlan Zhang, Stephen McLaughlin, J. Henkhaus, B. Leopold, M. Bielaszewska, R. Prager, P. Brzoska, Richard L. Moore, Simone Guenther, J. Rothberg, H. Karch   +19 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Massive Increase, Spread, and Exchange of Extended Spectrum {beta}-Lactamase-Encoding Genes Among Intestinal Enterobacteriaceae in Hospitalized Children With Severe Acute Malnutrition in Niger. [PDF]

, 2011
Background. From the time of CTX-M emergence, extended-spectrum β-lactamase-producing enterobacteria (ESBL-E) have spread worldwide in community settings as well as in hospitals, particularly in developing countries.
Andremont, A, Angebault, C, Armand-Lefèvre, L, Barbier, F, de Rekeneire, N, El Mniai, A, Hugede, H-C, Jacquier, H, Janssens, A-C, Page, A-L, Raskine, L, Ruppé, E, Sayadi, S, Woerther, P-L   +13 more
core   +2 more sources

Frequency and Distribution of Diarrhoeagenic Escherichia Coli Strains Isolated from Pediatric Patients with Diarrhoea in Bosnia and Herzegovina

Biomolecules & Biomedicine, 2009
Diarrhoeal disease is a major cause of illness and death among infants and young children worldwide. Among the Escherichia coli (E. coli) causing intestinal diseases, there are six well-described categories: enteroaggregative E.
Amela Dedeić-Ljubović, Mirsada Hukić, Daria Bekić, Amra Zvizdić   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Fabrication of graphene-based resistive sensor for eschericia coli bacteria sensing [PDF]

, 2018
The presence of fecal coliform bacteria like Escherichia coli (E. coli) in aquatic environments indicates that the water has been contaminated with the fecal material of human or animals. The risk of health threatening to humans become high when E.
Wibowo, Kusnanto Mukti
core  

Use of Desulfovibrio and Escherichia coli Pd-nanocatalysts in reduction of Cr(VI) and hydrogenolytic dehalogenation of polychlorinated biphenyls and used transformer oil [PDF]

, 2012
BACKGROUND Desulfovibrio spp. biofabricate metallic nanoparticles (e.g. ‘Bio-Pd’) which catalyse the reduction of Cr(VI) to Cr(III) and dehalogenate polychlorinated biphenyls (PCBs). Desulfovibrio spp.
Baxter-Plant, VS, Bennett, J. A., Deplanche, K, Humphries, AC, Macaskie, LE, Mikheenko, I. P., Redwood, MD, Wood, J.   +7 more
core   +1 more source