Results 161 to 170 of about 255,276 (245)

Examining E1 [PDF]

Nature Reviews Molecular Cell Biology, 2008
openaire   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source

Comprehensive Sampling Across Seasons and Habitats Revealed the Composition and Functional Attributes of Gut Microbiota Enterotypes in Subterranean Rodents. [PDF]

Ecol Evol
Ren S, Wang J, Guo D, Li J, Zhao Y, Han C, Nan X.   +6 more
europepmc   +1 more source

Latent Diffusion Process With Mechanistic Guidance For Designing Functionally Graded Metamaterials With Perfect Connectivity

Advanced Science, EarlyView.
A latent diffusion‐based framework is proposed for designing functionally graded metamaterials with perfect connectivity. By integrating vector‐quantized latent representations with mechanistic guidance, the framework enables accurate inverse design toward target elastic properties.
Jongbin Yu, Dosung Lee, Namjung Kim
wiley   +1 more source

In vivo activities of E1 elements in the insulin promoter. [PDF]

Commun Biol
Noguchi H, Miyagi-Shiohira C, Sadahira T, Watanabe M, Saitoh I.   +4 more
europepmc   +1 more source

Ion‐Driven Regulation of Ca2+ Flow by Ti/Zn Composite Activates ERK/MAPK Signaling and Maintains Mitochondrial Homeostasis to Promote Macrophage‐Mediated Bone Regeneration

Advanced Science, EarlyView.
A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang, Qiyue Zhang, Yueyang Qiu, Haocheng Suo, Zengqian Liu, Bing Bai, Qiang Wang, Qing Zhou   +7 more
wiley   +1 more source

Betulinic acid alleviates the inflammatory injury of osteoblasts in osteoporosis by augmenting autophagy via the AMPK-mTOR signaling pathway. [PDF]

Int J Mol Med
Zhao Y, Qu Z, Liu L, Zhang Y, Wang X, Zhang B, Gong Y, Yan L.   +7 more
europepmc   +1 more source

Symmetry‐Imposed Selection Rules for Excitations of Nontrivial Plasmonic Topologies

Advanced Science, EarlyView.
A unified group‐theory selection rule governs the excitation of vectorial nearfield topologies across three plasmonic spin states. Derived from first principles, it predicts spin–orbit vortex splitting and multidimensional nested vortices, confirmed by phase‐resolved in situ measurements.
Jie Yang, Pengyi Feng, Fei Han, Weijin Chen, Zhongwei Jin, Jincheng Ni, Yuanjie Yang, Anxue Zhang, Guy A. E. Vandenbosch, Niels Verellen, Ewald Janssens, Jiafu Wang, Benfeng Bai, Cheng‐Wei Qiu, Xuezhi Zheng   +14 more
wiley   +1 more source

Piezo1-activated mesenchymal stem cells-derived extracellular matrix hydrogel promotes the repair of osteoporotic bone defects through osteogenic and angiogenic coupling.

Regen Biomater
Yin H, Zhang W, Wei D, Chen J, Fu C, Ma X, Chen X, Xing X, Zhu Y, Tian H, Yang C, Zhang Y.   +11 more
europepmc   +1 more source

The Reactive Extrusion Cationization of Starches as a Novel Physicochemical Surface Modification Method. [PDF]

Biopolymers
Posada-Vélez MC, Millán-Malo BM, Barrón-García OY, Gaytán-Martínez M, Buitrón G.   +4 more
europepmc   +1 more source