Results 141 to 150 of about 309,262 (293)
Este trabalho tem como objetivo a especificação de um conjunto de módulos de circuito, capazes de executar as funções de multiplexação relativas Hierarquia Digital E1, do ITU-T.
Kaiser, Gustavo Weymar +1 more
core
RPTS predicted motif containing genes interact with hnRNP E1.
A) To assess the TGFβ induced serine-43 phosphorylation of hnRNP E1, we combined an immunoprecipitation and subsequent western blot analysis. Cytosolic hnRNP E1 was immunoprecipitated by α-hnRNP E1 / protein-A-sepharose, an antibody specific to the ...
Andrew S. Brown (110423) +2 more
core +1 more source
A nanoparticle‐cluster‐on‐mirror (NPcoM) serves as a functionally deterministic sub‐nanocavity that emulates picocavities, enabling extreme light–matter interactions and polaritonic phenomena. ABSTRACT Pushing nanoscale optical confinement to its ultimate limits defines the regime of nano‐cavity quantum electrodynamics (nano‐cQED), where light‐matter ...
Huatian Hu +10 more
wiley +1 more source
Generation of tagged cyclin E1 knock-In mice and analyses of cyclin E1-containing protein complexes.
(A and B) Targeting strategy to knock-in Flag and HA tags into the cyclin E1 locus to generate N-terminally tagged cyclin E1Ntag (A) and C-terminally tagged cyclin E1Ctag alleles (B). The exons are shown as green boxes, Flag tag as a blue box, and HA tag
Yaoyu E. Wang (646474) +12 more
core +1 more source
ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou +9 more
wiley +1 more source
Document and annexes that include, among other things, the planning of activities, coordination between packages, and dissemination efforts.
openaire +2 more sources
ARC3 levels are controlled by cytosolic and chloroplast proteolytic systems. PUB52 mediates ARC3 precursor ubiquitination and degradation in the cytosol, while CLPC1 promotes ARC3 degradation in chloroplasts, where ARC2 protects ARC3 from excessive breakdown. Disrupting these components causes chloroplast division defects, placing them upstream of ARC3.
Yang Yuan +5 more
wiley +1 more source
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng +8 more
wiley +1 more source
The inhibition of the proliferative stimulation exercised by estrogens on neoplastic cells is the goal of all endocrine therapies in breast cancer. Under various circumstances, e.g.
E. Bajetta +7 more
core +1 more source
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang +18 more
wiley +1 more source

