Results 21 to 30 of about 27,631 (200)

Ten Years Later: Lessons for DSGE Builders and Czech Policy Makers

Review of Economic Perspectives, 2019
We show an example of a small open economy – the Czech Republic – where the fiscal restriction was put in place between 2010 and 2013 in a negative output gap and zero lower bound on nominal interest rates.
Michl Aleš
doaj   +1 more source

Artemisinin Confers Neuroprotection against 6-OHDA-Induced Neuronal Injury In Vitro and In Vivo through Activation of the ERK1/2 Pathway

Molecules, 2023
Parkinson’s disease (PD) is an age-related, progressive neurodegenerative disease characterized by the gradual and massive loss of dopaminergic neurons in the substantia nigra pars compacta (SNc).
Qin Li, Shuai Li, Jiankang Fang, Chao Yang, Xia Zhao, Qing Wang, Wenshu Zhou, Wenhua Zheng   +7 more
doaj   +1 more source

Implementing Climate Change Adaptation Policies Across Scales: Challenges for Knowledge Coproduction in Andean Mountain Socio-ecosystems

Mountain Research and Development, 2022
The Andean region presents specific challenges related to its globally important natural heritage, the broad range of pressures on landscapes and ecosystems that accentuate the effects of climate change (CC), and a great diversity of institutional ...
Emilie Dupuits, Luis Daniel Llambí, Manuel Peralvo   +2 more
doaj   +1 more source

Structural basis of the monkeypox virus mRNA cap N7 methyltransferase complex

Emerging Microbes and Infections
The global outbreak of Mpox, caused by the monkeypox virus (MPXV), has attracted international attention and become another major infectious disease event after COVID-19.
Anke Chen, Ning Fang, Zhifei Zhang, Yiqing Wen, Yajie Shen, Yanjie Zhang, Lu Zhang, Guoping Zhao, Jin Ding, Jixi Li   +9 more
doaj   +1 more source

Phase separation is regulated by post-translational modifications and participates in the developments of human diseases

Heliyon
Liquid-liquid phase separation (LLPS) of intracellular proteins has emerged as a hot research topic in recent years. Membrane-less and liquid-like condensates provide dense spaces that ensure cells to high efficiently regulate genes transcription and ...
Weibo Zhang, Zhengfeng Li, Xianju Wang, Ting Sun   +3 more
doaj   +1 more source

An assessment of adequacy of pre-retirement savings for sustainable retirement income under the Nigerian 2014 pension scheme

Journal of Economics and Management, 2019
Aim/purpose – The main objectives of this article are to estimate percentage of preretirement savings that is needed, based on the current salary scale, to sustain academic and non-academic staff of Federal Universities in Nigeria in retirement using ...
Sogunro Ashim Babatunde, Adeleke Ismaila Adedeji, Ayorinde Richard Olusegun   +2 more
doaj   +1 more source

Dynamic distribution of gut microbiota during embryonic development in chicken

Poultry Science, 2020
The gut microbiota is a complex ecological community and widely recognized in many aspects of research, but little is known on the relation between gut microbiota and embryonic development in chickens.
Fisayo T. Akinyemi, Jinmei Ding, Hao Zhou, Ke Xu, Chuan He, Chengxiao Han, Yuming Zheng, Huaixi Luo, Kaixuan Yang, Caiju Gu, Qizhong Huang, He Meng   +11 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Does Demonetisation in India Achieve its Objectives?

Studia Ekonomiczne i Regionalne, 2022
Subject and purpose of work: T he d emonetisation e xercise i n I ndia a imed t o t ackle t he problems of black money, fake currency, corruption, and terror funding.
Azeez N.P. Abdul
doaj   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source