Dynamic control of selectivity in the ubiquitination pathway revealed by an ASP to GLU substitution in an intra-molecular salt-bridge network [PDF]
, 2012 Ubiquitination relies on a subtle balance between selectivity and promiscuity achieved through specific interactions between ubiquitin-conjugating enzymes (E2s) and ubiquitin ligases (E3s).
Bonvin, Alexandre M. J. J. +14 more
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Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors [PDF]
, 2010 Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Christiane Brohm +25 more
core +2 more sources
Biotechnology & Biotechnological Equipment, 2019 In this study, we investigated environmental oestrogen 17β-estradiol (E2) degradation by a mixed culture of Rhodococcus equi DSSKP-R-001(RS) and Comamonas testosteroni QYY20150409(CT).
Yu Wang +5 more
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Jurnal Rekayasa Kimia & Lingkungan, 2023 Fermentation has been developed to produce a distinctive taste in food, one of which is coffee. Fermentation affects the quality and taste of coffee in coffee beans.
Madyawati Latief +3 more
doaj +1 more source
Cyclooxygenases and prostaglandin E2 receptors in growth plate chondrocytes in vitro and in situ : prostaglandin E2 dependent proliferation of growth plate chondrocytes [PDF]
, 2006 Prostaglandin E2 (PGE2) plays an important role in bone development and metabolism. To interfere therapeutically in the PGE2 pathway, however, knowledge about the involved enzymes (cyclooxygenases) and receptors (PGE2 receptors) is essential.
Nüsing, Rolf M. +9 more
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The fanconi anemia DNA repair pathway is regulated by an interaction between ubiquitin and the E2-like fold domain of FANCL [PDF]
, 2015 The Fanconi Anemia (FA) DNA repair pathway is essential for the recognition and repair of DNA interstrand crosslinks (ICL). Inefficient repair of these ICL can lead to leukemia and bone marrow failure.
Howard, Mark J. +8 more
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E2-T179N attenuates MAYV replication and tissue pathology in mice.
, 2023 Four-week-old CD-1 mice were infected with 105 PFU in 50 μL via injection to the left, hind footpad. A: Viral load in serum was assessed daily by plaque assay. Statistical comparisons were made using multiple unpaired t tests with correction for multiple
Rafael Elias Marques (9953951) +22 more
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Applied Food ResearchNon-destructive quality evaluation techniques are vital in 3D visualization and quantification of microstructural changes in micronized pulse kernels.
Bailey Paziuk +2 more
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SUMO conjugation – a mechanistic view
Biomolecular Concepts, 2017 The regulation of protein fate by modification with the small ubiquitin-related modifier (SUMO) plays an essential and crucial role in most cellular pathways.
Pichler Andrea +3 more
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The Shape of Human Red Blood Cells Suspended in Autologous Plasma and Serum
Cells, 2022 (1) Background: In almost all studies of the shape of the human red blood cell (RBC), the suspending medium was a salt solution supplemented with albumin.
Thomas M. Fischer
doaj +1 more source