Results 41 to 50 of about 419,747 (241)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
e2's Survey on Values and Attitudes 2016
, 2019 Tutkimuksessa selvitettiin suomalaisten näkemyksiä keskusteluilmapiiristä ja sen vaikutuksista osallistumiseen. Samalla kartoitettiin vastaajien näkemyksiä yhteiskunnan ilmapiiristä, demokratiasta, hyvinvoinnista, turvallisuudesta, maahanmuutosta ...
Think Tank e2 +3 more
core +1 more source
Modeling Local Variations in Intermarriage
Mathematics, 2022 We utilized all Spanish marriage records available at the municipality level from 2005–2007 to model spatial variations in intermarriage. We constructed a spatial regime zero-inflated Poisson model and grouped-data probit model, with spatially lagged ...
Albert Esteve +2 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Cardiac characteristics of sham, OVX, OVX-E2 and OVX-E2-EX groups.
, 2018 Cardiac characteristics of sham, OVX, OVX-E2 and OVX-E2-EX groups.
Yi-Yuan Lin (6107192) +9 more
core +1 more source
Hepatitis C virus (HCV) infection may elicit neutralizing antibodies targeting epitopes conserved in all viral genotypes [PDF]
, 2009 Anti-hepatitis C virus (HCV) cross-neutralizing human monoclonal antibodies, directed against conserved epitopes on surface E2 glycoprotein, are central tools for understanding virus-host interplay, and for planning strategies for prevention and ...
Patel, Ah +39 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Eesti Rakenduslingvistika Ühingu AastaraamatThe article describes a pilot Estonian grammar game developed for young learners’ L1 and L2 acquisition of the Estonian go + destination ‘minema + kohasõna’ construction created on the ALPA Kids platform and explores the general possibilities of ...
Kelly Lilles
doaj +1 more source
Fragmentation of Millimeter-Size Hypervelocity Projectiles on Combined Mesh-Plate Bumpers
Advances in Materials Science and Engineering, 2017 This numerical study evaluates the concept of a combined mesh-plate bumper as a shielding system protecting unmanned spacecraft from small (1 mm) orbital debris impacts.
Aleksandr Cherniaev, Igor Telichev
doaj +1 more source