Results 51 to 60 of about 45,315 (189)

ZFPL1 Promotes Colorectal Cancer Progression by Stabilizing ASS1 to Drive the Urea Cycle and M2 Macrophage‐Mediated Metastatic Colonization

Advanced Science, Volume 12, Issue 46, December 11, 2025.
ScRNA‐seq reveals ZFPL1‐specific enrichment in malignant CRC cells. Mechanistically, ZFPL1 stabilizes ASS1 by blocking K57 ubiquitination, activating urea cycle metabolism to drive progression. ZFPL1 inhibition reprograms the TME by suppressing M2 macrophages polarization and promotion M1 macrophages, thereby inhibiting CRC liver metastasis ...
Xiangjun Qian, Chenxi Xie, Beilin Zhang, Hengsong Cao, Zhengqing Lu, Li Liu, Shipeng Dai, Xiaoqian Wang, Xiaokai Zhang, Feng Han, Yanyan Liu, Haibo Yu, Weiwei Tang, Jinxue Zhou, Xiaopei Hao   +14 more
wiley   +1 more source

Inequality and Informal Economy: The Moderating Role of Financial Technology

ECONOMICS
Increasing income distribution gaps have become a global socio-economic problem accentuating economic and social exclusion with a potential of generating declining social cohesion and political stability.
Magwedere Margaret Rutendo, Marozva Godfrey   +1 more
doaj   +1 more source

Effectiveness of a Self-Guided Web-Based Cannabis Treatment Program: Randomized Controlled Trial

Journal of Medical Internet Research, 2013
BackgroundSelf-help strategies offer a promising way to address problems with access to and stigma associated with face-to-face drug and alcohol treatment, and the Internet provides an excellent delivery mode for such strategies.
Rooke, Sally, Copeland, Jan, Norberg, Melissa, Hine, Donald, McCambridge, Jim   +4 more
doaj   +1 more source

Generators of simple modular Lie superalgebras

, 2012
Let $X$ be one of the finite-dimensional simple graded Lie superalgebras of Cartan type $W, S, H, K, HO, KO, SHO$ or $SKO$ over an algebraically closed field of characteristic $p>3$.
Kuranishi M., Liming Tang, Wende Liu, Zhang R.B.   +3 more
core   +1 more source

Lack of ERG-antibody in Benign Mimickers of Prostate Cancer

Folia Medica, 2016
Introduction: Prostate carcinoma (PC) is the second most diagnosed cancer in men worldwide. Prostate tissue in needle biopsy expresses a wide variety of architectural patterns some of which are difficult to interpret. Immunohistochemical markers, such as
Bachurska Svitlana Y., Staykov Dmitriy G., Ivanov Georgi P., Belovezhdov Veselin T.   +3 more
doaj   +1 more source

Myeloblasts transformed by the avian acute leukemia virus E26 are hormone-dependent for growth and for the expression of a putative myb-containing protein, p135 E26. [PDF]

The EMBO Journal, 1982
Avian leukemia virus E26 contains the myb oncogene and transforms erythroid and myeloid hematopoietic cells in vivo and in vitro. E26-transformed nonproducer myeloblasts but not avian erythroleukemia virus (AEV)-transformed erythroblasts nor MC29-transformed macrophages were shown to be dependent for growth on factor(s) present in supernatants from ...
H, Beug, M J, Hayman, T, Graf
openaire   +2 more sources

Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Gege Li, Fangfang Li, Yang Tang, Siyu Guo, Yihan Yao, Yuan Fang, Bicheng Zhang, Yu Jiang, Jing Wang, Dang Wu, Jianxia Cheng, Zhihui Huang, Zengfeng Xin, Ting Zhang   +13 more
wiley   +1 more source

Ulrich line bundles on Enriques surfaces with a polarization of degree four

, 2017
In this paper, we prove the existence of an Enriques surface with a polarization of degree four with an Ulrich bundle of rank one. As a consequence, we prove that general polarized Enriques surfaces of degree four, with the same numerical polarization ...
Aprodu, M., Kim, Y.
core   +2 more sources

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, Volume 58, Issue 12, December 2025.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

A systematic literature review of illicit financial flows and money laundering: Current state of research and estimation methods

Journal of Economics and Management
Aim/purpose – The goal of the paper is to examine the current state of research on illicit financial flows (IFF) and money laundering (ML) with a specific focus on detection and estimation methods.
Popik-Mazur Anna
doaj   +1 more source