Results 1 to 10 of about 177,226 (290)
Science, 1982 In his letter of 15 October (p. 214), John W. Littlefield points out that the cell line NIH 3T3 is an imperfect recipient for experiments designed to capture "oncogenes" by gene transfer from tumor cell genomic DNA. I agree.
Pollack, Robert
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Oncogenes in immune cells as potential therapeutic targets
ImmunoTargets and Therapy, 2018 Gulnur K Zakiryanova,1 Sarah Wheeler,2 Michael R Shurin2 1Department Biophysics and Biomedicine, Faculty Biology and Biotechnology, Al-Farabi Kazakh National University, Almaty, Kazakhstan; 2Division of Clinical Immunopathology, Department of Pathology ...
Zakiryanova GK, Wheeler S, Shurin MR
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Complex landscape of somatic copy number alterations in head and neck paragangliomas [PDF]
Frontiers in EndocrinologyBackgroundCopy number alterations (CNAs) drive cancer by amplifying oncogenes and deleting tumor suppressor genes. Although CNA patterns are well-studied in common cancers, they remain poorly characterized in rare tumors.MethodsIn this study, we employed
Vladislav S. Pavlov +11 more
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New England Journal of Medicine, 1995 Discusses how the chemical alteration of oncogenes in human cells causes the growth of cancerous tumors. Toxic substances, radiation, viruses, and inherited genetic defects are examined as factors causing such alteration.
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Journal of Immunology Research, 2022 Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, and the patients are generally diagnosed with distant metastasis. Liver is one of the preferred organs of distant metastasis, and liver metastasis is the leading cause of ...
Yue Sun +8 more
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Journal of Immunology Research, 2022 Hepatocellular carcinoma (HCC) is the most common type of primary liver malignancy with poor prognosis worldwide. Emerging evidences demonstrated critical roles of lipid de novo synthesis in HCC progression, yet its regulatory mechanisms are not fully ...
Lei Zhu +7 more
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Frontiers in Oncology, 2022 The incidence and mortality of Prostate Cancer (PCa) worldwide correlate with age and bad dietary habits. Previously, we investigated the mRNA/miRNA role on PCa development and progression using high fat diet (HFD) fed mice.
Rocío Belén Duca +7 more
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Emerging Biomarkers for Predicting Bladder Cancer Lymph Node Metastasis
Frontiers in Oncology, 2021 Bladder cancer is one of the leading causes of cancer deaths worldwide. Early detection of lymph node metastasis of bladder cancer is essential to improve patients’ prognosis and overall survival.
Chunyu Zhang +11 more
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Molecules, 2023 The c-MYC oncogene regulates multiple cellular activities and is a potent driver of many highly aggressive human cancers, such as leukemia and triple-negative breast cancer.
Min Zhou +4 more
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