Results 11 to 20 of about 177,226 (290)

Anticancer Effect of Fluorouracil and Gum-Based Cerium Oxide Nanoparticles on Human Malignant Colon Carcinoma Cell Line (Caco2) [PDF]

open access: yesCell Journal, 2023
Objective: We investigated whether co-incubation of 5-FU and gum-based cerium oxide nanoparticles (CeO2 NPs) would improve half-maximal inhibitory concentration (IC50) and apoptosis in the Caco-2 cancer cell lineMaterials and Methods: In this ...
Zahra Keramati   +3 more
doaj   +1 more source

Annotation of Genes Having Candidate Somatic Mutations in Acute Myeloid Leukemia with Whole-Exome Sequencing Using Concept Lattice Analysis [PDF]

open access: yesGenomics & Informatics, 2013
In cancer genome studies, the annotation of newly detected oncogene/tumor suppressor gene candidates is a challenging process. We propose using concept lattice analysis for the annotation and interpretation of genes having candidate somatic mutations in ...
Kye Hwa Lee, Jae Hyeun Lim, Ju Han Kim
doaj   +1 more source

Pterostilbene Changes Epigenetic Marks at Enhancer Regions of Oncogenes in Breast Cancer Cells

open access: yesAntioxidants, 2021
Epigenetic aberrations are linked to sporadic breast cancer. Interestingly, certain dietary polyphenols with anti-cancer effects, such as pterostilbene (PTS), have been shown to regulate gene expression by altering epigenetic patterns.
Sadaf Harandi-Zadeh   +11 more
doaj   +1 more source

Gap-enhanced Raman tags for physically unclonable anticounterfeiting labels

open access: yesNature Communications, 2020
Physical unclonable functions with inherent randomness are promising candidates for secure labeling systems. Here the authors demonstrate such a function using gap-enhanced Raman tags to create high-capacity and high-security labels for ...
Yuqing Gu   +5 more
doaj   +1 more source

Leukobiopsy – A Possible New Liquid Biopsy Platform for Detecting Oncogenic Mutations

open access: yesFrontiers in Pharmacology, 2020
Detection of unique oncogenic alterations encoded by the sequence or biochemical modification in cancer-associated transforming macromolecules has revolutionized diagnosis, classification and management of human cancers.
Shilpa Chennakrishnaiah   +3 more
doaj   +1 more source

YAP-Dependent BiP Induction Is Involved in Nicotine-Mediated Oral Cancer Malignancy

open access: yesCells, 2021
Cigarette smoking is a significant risk factor for the development and progression of oral cancer. Previous studies have reported an association between nicotine and malignancy in oral cancer.
Chu-Yen Chien   +9 more
doaj   +1 more source

Cloning of the genes for non-medullary thyroid cancer: Methods and advances [PDF]

open access: yesArchive of Oncology, 2006
In last ten years, significant advances have occurred in thyroid endocrinology, as a consequence of the generalized use of molecular biology techniques.
Stankov Karmen, Romeo Giovanni
doaj   +1 more source

Mutations in a High-Grade Micropapillary Urothelial Carcinoma of the Renal Pelvis: A Case Report

open access: yesCase Reports in Oncology, 2023
Micropapillary urothelial carcinoma (MPUC) of the renal pelvis is an upper tract urothelial carcinoma originating in the renal pelvis region. Few genetic studies are available, and the mechanism of pathogenesis of genetically driven models is unclear. We
Kalyan Ram Uppaluri   +7 more
doaj   +1 more source

Genetically manipulating endogenous Kras levels and oncogenic mutations in vivo influences tissue patterning of murine tumorigenesis

open access: yeseLife, 2022
Despite multiple possible oncogenic mutations in the proto-oncogene KRAS, unique subsets of these mutations are detected in different cancer types. As KRAS mutations occur early, if not being the initiating event, these mutational biases are ostensibly a
Özgün Le Roux   +8 more
doaj   +1 more source

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