Results 11 to 20 of about 239,426 (300)

Diet-Induced Obesity Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma via CX3CL1/CX3CR1 Axis

open access: yesJournal of Immunology Research, 2022
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, and the patients are generally diagnosed with distant metastasis. Liver is one of the preferred organs of distant metastasis, and liver metastasis is the leading cause of ...
Yue Sun   +8 more
doaj   +1 more source

Tuftelin 1 Facilitates Hepatocellular Carcinoma Progression through Regulation of Lipogenesis and Focal Adhesion Maturation

open access: yesJournal of Immunology Research, 2022
Hepatocellular carcinoma (HCC) is the most common type of primary liver malignancy with poor prognosis worldwide. Emerging evidences demonstrated critical roles of lipid de novo synthesis in HCC progression, yet its regulatory mechanisms are not fully ...
Lei Zhu   +7 more
doaj   +1 more source

Hsa-miR-133a-3p, miR-1-3p, GOLPH3 and JUP combination results in a good biomarker to distinguish between prostate cancer and non-prostate cancer patients

open access: yesFrontiers in Oncology, 2022
The incidence and mortality of Prostate Cancer (PCa) worldwide correlate with age and bad dietary habits. Previously, we investigated the mRNA/miRNA role on PCa development and progression using high fat diet (HFD) fed mice.
Rocío Belén Duca   +7 more
doaj   +1 more source

Emerging Biomarkers for Predicting Bladder Cancer Lymph Node Metastasis

open access: yesFrontiers in Oncology, 2021
Bladder cancer is one of the leading causes of cancer deaths worldwide. Early detection of lymph node metastasis of bladder cancer is essential to improve patients’ prognosis and overall survival.
Chunyu Zhang   +11 more
doaj   +1 more source

Modes of Action of a Novel c-MYC Inhibiting 1,2,4-Oxadiazole Derivative in Leukemia and Breast Cancer Cells

open access: yesMolecules, 2023
The c-MYC oncogene regulates multiple cellular activities and is a potent driver of many highly aggressive human cancers, such as leukemia and triple-negative breast cancer.
Min Zhou   +4 more
doaj   +1 more source

Anticancer Effect of Fluorouracil and Gum-Based Cerium Oxide Nanoparticles on Human Malignant Colon Carcinoma Cell Line (Caco2) [PDF]

open access: yesCell Journal, 2023
Objective: We investigated whether co-incubation of 5-FU and gum-based cerium oxide nanoparticles (CeO2 NPs) would improve half-maximal inhibitory concentration (IC50) and apoptosis in the Caco-2 cancer cell lineMaterials and Methods: In this ...
Zahra Keramati   +3 more
doaj   +1 more source

Annotation of Genes Having Candidate Somatic Mutations in Acute Myeloid Leukemia with Whole-Exome Sequencing Using Concept Lattice Analysis [PDF]

open access: yesGenomics & Informatics, 2013
In cancer genome studies, the annotation of newly detected oncogene/tumor suppressor gene candidates is a challenging process. We propose using concept lattice analysis for the annotation and interpretation of genes having candidate somatic mutations in ...
Kye Hwa Lee, Jae Hyeun Lim, Ju Han Kim
doaj   +1 more source

Pterostilbene Changes Epigenetic Marks at Enhancer Regions of Oncogenes in Breast Cancer Cells

open access: yesAntioxidants, 2021
Epigenetic aberrations are linked to sporadic breast cancer. Interestingly, certain dietary polyphenols with anti-cancer effects, such as pterostilbene (PTS), have been shown to regulate gene expression by altering epigenetic patterns.
Sadaf Harandi-Zadeh   +11 more
doaj   +1 more source

Gap-enhanced Raman tags for physically unclonable anticounterfeiting labels

open access: yesNature Communications, 2020
Physical unclonable functions with inherent randomness are promising candidates for secure labeling systems. Here the authors demonstrate such a function using gap-enhanced Raman tags to create high-capacity and high-security labels for ...
Yuqing Gu   +5 more
doaj   +1 more source

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