Results 11 to 20 of about 241,519 (301)

Leukobiopsy – A Possible New Liquid Biopsy Platform for Detecting Oncogenic Mutations

open access: yesFrontiers in Pharmacology, 2020
Detection of unique oncogenic alterations encoded by the sequence or biochemical modification in cancer-associated transforming macromolecules has revolutionized diagnosis, classification and management of human cancers.
Shilpa Chennakrishnaiah   +3 more
doaj   +1 more source

YAP-Dependent BiP Induction Is Involved in Nicotine-Mediated Oral Cancer Malignancy

open access: yesCells, 2021
Cigarette smoking is a significant risk factor for the development and progression of oral cancer. Previous studies have reported an association between nicotine and malignancy in oral cancer.
Chu-Yen Chien   +9 more
doaj   +1 more source

Gap-enhanced Raman tags for physically unclonable anticounterfeiting labels

open access: yesNature Communications, 2020
Physical unclonable functions with inherent randomness are promising candidates for secure labeling systems. Here the authors demonstrate such a function using gap-enhanced Raman tags to create high-capacity and high-security labels for ...
Yuqing Gu   +5 more
doaj   +1 more source

Cloning of the genes for non-medullary thyroid cancer: Methods and advances [PDF]

open access: yesArchive of Oncology, 2006
In last ten years, significant advances have occurred in thyroid endocrinology, as a consequence of the generalized use of molecular biology techniques.
Stankov Karmen, Romeo Giovanni
doaj   +1 more source

Mutations in a High-Grade Micropapillary Urothelial Carcinoma of the Renal Pelvis: A Case Report

open access: yesCase Reports in Oncology, 2023
Micropapillary urothelial carcinoma (MPUC) of the renal pelvis is an upper tract urothelial carcinoma originating in the renal pelvis region. Few genetic studies are available, and the mechanism of pathogenesis of genetically driven models is unclear. We
Kalyan Ram Uppaluri   +7 more
doaj   +1 more source

Genetically manipulating endogenous Kras levels and oncogenic mutations in vivo influences tissue patterning of murine tumorigenesis

open access: yeseLife, 2022
Despite multiple possible oncogenic mutations in the proto-oncogene KRAS, unique subsets of these mutations are detected in different cancer types. As KRAS mutations occur early, if not being the initiating event, these mutational biases are ostensibly a
Özgün Le Roux   +8 more
doaj   +1 more source

Tumor biology: molecular genetics mechanisms of initiation, promotion and progression

open access: yesJournal of Education, Health and Sport, 2022
For all tumors, regardless of type and tissue, there are a number of common features. These include high proliferative activity, disturbances in the mechanisms of apoptosis and "invisibility" for the cells of the immune system. At the basis of all these
Elizaveta Ageeva   +9 more
doaj   +1 more source

Regulation of Endoplasmic Reticulum–Mitochondria Ca2+ Transfer and Its Importance for Anti-Cancer Therapies

open access: yesFrontiers in Oncology, 2017
Inter-organelle membrane contact sites are emerging as major sites for the regulation of intracellular Ca2+ concentration and distribution. Here, extracellular stimuli operate on a wide array of channels, pumps, and ion exchangers to redistribute ...
Gaia Pedriali   +6 more
doaj   +1 more source

Oncogenic Processes [PDF]

open access: yesBioMed Research International, 2014
No abstract available.
Rita de Cassia Stocco   +3 more
openaire   +4 more sources

Fast Prototyping Microfluidics: Integrating Droplet Digital Lamp for Absolute Quantification of Cancer Biomarkers

open access: yesSensors, 2020
Microfluidic (MF) advancements have been leveraged toward the development of state-of-the-art platforms for molecular diagnostics, where isothermal amplification schemes allow for further simplification of DNA detection and quantification protocols.
Beatriz Oliveira   +6 more
doaj   +1 more source

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