Results 21 to 30 of about 177,226 (290)
Tumor biology: molecular genetics mechanisms of initiation, promotion and progression
Journal of Education, Health and Sport, 2022 For all tumors, regardless of type and tissue, there are a number of common features. These include high proliferative activity, disturbances in the mechanisms of apoptosis and "invisibility" for the cells of the immune system. At the basis of all these
Elizaveta Ageeva +9 more
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BioMed Research International, 2014 No abstract available.
Rita de Cassia Stocco +3 more
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Ultrabright gap-enhanced Raman tags for high-speed bioimaging
Nature Communications, 2019 The speed of surface-enhanced Raman spectroscopy (SERS) imaging is generally limited due to low Raman signals. Here, the authors develop bright gap-enhanced Raman tags with external hot spots and demonstrate their use in fast near-infrared bioimaging.
Yuqing Zhang +4 more
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Frontiers in Oncology, 2017 Inter-organelle membrane contact sites are emerging as major sites for the regulation of intracellular Ca2+ concentration and distribution. Here, extracellular stimuli operate on a wide array of channels, pumps, and ion exchangers to redistribute ...
Gaia Pedriali +6 more
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Scandinavian Journal of Gastroenterology, 1985 The central problem in cancer therapy is the poor selectivity of current systemic agents against the common solid tumours. The demonstration that unique segments of DNA, constant in location and conserved in evolution are involved in growth control opens new avenues for basic and clinical research.
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Sensors, 2020 Microfluidic (MF) advancements have been leveraged toward the development of state-of-the-art platforms for molecular diagnostics, where isothermal amplification schemes allow for further simplification of DNA detection and quantification protocols.
Beatriz Oliveira +6 more
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Brief inactivation of c-Myc is not sufficient for sustained regression of c-Myc-induced tumours of pancreatic islets and skin epidermis [PDF]
, 2004 Background Tumour regression observed in many conditional mouse models following oncogene inactivation provides the impetus to develop, and a platform to preclinically evaluate, novel therapeutics to inactivate specific oncogenes.
Abouna, Sylvie +11 more
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Molecules, 2013 G-quadruplexes are therapeutically important biological targets. In this report, we present biophysical studies of neomycin-Hoechst 33258 conjugates binding to a G-quadruplex derived from the C-myc promoter sequence.
Nihar Ranjan, Dev P. Arya
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Designer nucleases to treat malignant cancers driven by viral oncogenes
, 2021 Viral oncogenic transformation of healthy cells into a malignant state is a well-established phenomenon but took decades from the discovery of tumor-associated viruses to their accepted and established roles in oncogenesis.
Scott, TA, Morris, KV
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Proto‐oncogenes and oncogenes in epidermal neoplasia [PDF]
Experimental Dermatology, 1995 Abstract This review briefly will focus on the role of selected proto‐onco‐genes and their activated forms during the regulation of cell proliferation, cell death and tumor formation in the epidermis. In addition, the multiple and complex functions of these proteins in normal as well as transformed cells will be discussed.
M M, Simon, G, Sliutz, T A, Luger
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