Annotation of Genes Having Candidate Somatic Mutations in Acute Myeloid Leukemia with Whole-Exome Sequencing Using Concept Lattice Analysis [PDF]
Genomics & Informatics, 2013 In cancer genome studies, the annotation of newly detected oncogene/tumor suppressor gene candidates is a challenging process. We propose using concept lattice analysis for the annotation and interpretation of genes having candidate somatic mutations in ...
Kye Hwa Lee, Jae Hyeun Lim, Ju Han Kim
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Oncogenes, proto-oncogenes, and lineage restriction of cancer stem cells [PDF]
, 2021 In principle, an oncogene is a cellular gene (proto-oncogene) that is dysfunctional, due to mutation and fusion with another gene or overexpression. Generally, oncogenes are viewed as deregulating cell proliferation or suppressing apoptosis in driving ...
Brown, Geoff, Geoffrey Brown
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Pterostilbene Changes Epigenetic Marks at Enhancer Regions of Oncogenes in Breast Cancer Cells
Antioxidants, 2021 Epigenetic aberrations are linked to sporadic breast cancer. Interestingly, certain dietary polyphenols with anti-cancer effects, such as pterostilbene (PTS), have been shown to regulate gene expression by altering epigenetic patterns.
Sadaf Harandi-Zadeh +11 more
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Gap-enhanced Raman tags for physically unclonable anticounterfeiting labels
Nature Communications, 2020 Physical unclonable functions with inherent randomness are promising candidates for secure labeling systems. Here the authors demonstrate such a function using gap-enhanced Raman tags to create high-capacity and high-security labels for ...
Yuqing Gu +5 more
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Leukobiopsy – A Possible New Liquid Biopsy Platform for Detecting Oncogenic Mutations
Frontiers in Pharmacology, 2020 Detection of unique oncogenic alterations encoded by the sequence or biochemical modification in cancer-associated transforming macromolecules has revolutionized diagnosis, classification and management of human cancers.
Shilpa Chennakrishnaiah +3 more
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YAP-Dependent BiP Induction Is Involved in Nicotine-Mediated Oral Cancer Malignancy
Cells, 2021 Cigarette smoking is a significant risk factor for the development and progression of oral cancer. Previous studies have reported an association between nicotine and malignancy in oral cancer.
Chu-Yen Chien +9 more
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Cloning of the genes for non-medullary thyroid cancer: Methods and advances [PDF]
Archive of Oncology, 2006 In last ten years, significant advances have occurred in thyroid endocrinology, as a consequence of the generalized use of molecular biology techniques.
Stankov Karmen, Romeo Giovanni
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Mutations in a High-Grade Micropapillary Urothelial Carcinoma of the Renal Pelvis: A Case Report
Case Reports in Oncology, 2023 Micropapillary urothelial carcinoma (MPUC) of the renal pelvis is an upper tract urothelial carcinoma originating in the renal pelvis region. Few genetic studies are available, and the mechanism of pathogenesis of genetically driven models is unclear. We
Kalyan Ram Uppaluri +7 more
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eLife, 2022 Despite multiple possible oncogenic mutations in the proto-oncogene KRAS, unique subsets of these mutations are detected in different cancer types. As KRAS mutations occur early, if not being the initiating event, these mutational biases are ostensibly a
Özgün Le Roux +8 more
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Tumor biology: molecular genetics mechanisms of initiation, promotion and progression
Journal of Education, Health and Sport, 2022 For all tumors, regardless of type and tissue, there are a number of common features. These include high proliferative activity, disturbances in the mechanisms of apoptosis and "invisibility" for the cells of the immune system. At the basis of all these
Elizaveta Ageeva +9 more
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