Results 21 to 30 of about 239,426 (300)
Leukobiopsy – A Possible New Liquid Biopsy Platform for Detecting Oncogenic Mutations
Frontiers in Pharmacology, 2020 Detection of unique oncogenic alterations encoded by the sequence or biochemical modification in cancer-associated transforming macromolecules has revolutionized diagnosis, classification and management of human cancers.
Shilpa Chennakrishnaiah +3 more
doaj +1 more source
YAP-Dependent BiP Induction Is Involved in Nicotine-Mediated Oral Cancer Malignancy
Cells, 2021 Cigarette smoking is a significant risk factor for the development and progression of oral cancer. Previous studies have reported an association between nicotine and malignancy in oral cancer.
Chu-Yen Chien +9 more
doaj +1 more source
Cloning of the genes for non-medullary thyroid cancer: Methods and advances [PDF]
Archive of Oncology, 2006 In last ten years, significant advances have occurred in thyroid endocrinology, as a consequence of the generalized use of molecular biology techniques.
Stankov Karmen, Romeo Giovanni
doaj +1 more source
Mutations in a High-Grade Micropapillary Urothelial Carcinoma of the Renal Pelvis: A Case Report
Case Reports in Oncology, 2023 Micropapillary urothelial carcinoma (MPUC) of the renal pelvis is an upper tract urothelial carcinoma originating in the renal pelvis region. Few genetic studies are available, and the mechanism of pathogenesis of genetically driven models is unclear. We
Kalyan Ram Uppaluri +7 more
doaj +1 more source
eLife, 2022 Despite multiple possible oncogenic mutations in the proto-oncogene KRAS, unique subsets of these mutations are detected in different cancer types. As KRAS mutations occur early, if not being the initiating event, these mutational biases are ostensibly a
Özgün Le Roux +8 more
doaj +1 more source
SomInaClust: detection of cancer genes based on somatic mutation patterns of inactivation and clustering [PDF]
, 2015 Background: With the advances in high throughput technologies, increasing amounts of cancer somatic mutation data are being generated and made available.
Fierro Gutierrez, Ana Carolina Elisa +3 more
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Mutations and amplification of oncogenes in endometrial cancer [PDF]
, 1999 Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 ...
An, Han-Xiang +5 more
core +1 more source
Is Lactate an Oncometabolite? Evidence Supporting a Role for Lactate in the Regulation of Transcriptional Activity of Cancer-Related Genes in MCF7 Breast Cancer Cells. [PDF]
, 2019 Lactate is a ubiquitous molecule in cancer. In this exploratory study, our aim was to test the hypothesis that lactate could function as an oncometabolite by evaluating whether lactate exposure modifies the expression of oncogenes, or genes encoding ...
Brooks, George A +4 more
core +1 more source
BioMed Research International, 2014 No abstract available.
Rita de Cassia Stocco +3 more
openaire +4 more sources
Scandinavian Journal of Gastroenterology, 1985 The central problem in cancer therapy is the poor selectivity of current systemic agents against the common solid tumours. The demonstration that unique segments of DNA, constant in location and conserved in evolution are involved in growth control opens new avenues for basic and clinical research.
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