Results 31 to 40 of about 30,889 (150)
Ultrabright gap-enhanced Raman tags for high-speed bioimaging
The speed of surface-enhanced Raman spectroscopy (SERS) imaging is generally limited due to low Raman signals. Here, the authors develop bright gap-enhanced Raman tags with external hot spots and demonstrate their use in fast near-infrared bioimaging.
Yuqing Zhang +4 more
doaj +1 more source
Inter-organelle membrane contact sites are emerging as major sites for the regulation of intracellular Ca2+ concentration and distribution. Here, extracellular stimuli operate on a wide array of channels, pumps, and ion exchangers to redistribute ...
Gaia Pedriali +6 more
doaj +1 more source
No abstract available.
Rita de Cassia Stocco +3 more
openaire +4 more sources
Novel oncogenes and tumor suppressor genes in hepatocellular carcinoma [PDF]
Hepatocellular carcinoma (HCC) is a very deadly disease. HCC initiation and progression involve multiple genetic events, including the activation of proto-oncogenes and disruption of the function of specific tumor suppressor genes.
Breslin S J, Peter +5 more
core +1 more source
Microfluidic (MF) advancements have been leveraged toward the development of state-of-the-art platforms for molecular diagnostics, where isothermal amplification schemes allow for further simplification of DNA detection and quantification protocols.
Beatriz Oliveira +6 more
doaj +1 more source
G-quadruplexes are therapeutically important biological targets. In this report, we present biophysical studies of neomycin-Hoechst 33258 conjugates binding to a G-quadruplex derived from the C-myc promoter sequence.
Nihar Ranjan, Dev P. Arya
doaj +1 more source
Proto‐oncogenes and oncogenes in epidermal neoplasia [PDF]
Abstract This review briefly will focus on the role of selected proto‐onco‐genes and their activated forms during the regulation of cell proliferation, cell death and tumor formation in the epidermis. In addition, the multiple and complex functions of these proteins in normal as well as transformed cells will be discussed.
M M, Simon, G, Sliutz, T A, Luger
openaire +2 more sources
The central problem in cancer therapy is the poor selectivity of current systemic agents against the common solid tumours. The demonstration that unique segments of DNA, constant in location and conserved in evolution are involved in growth control opens new avenues for basic and clinical research.
+8 more sources
The Mutant p53-Driven Secretome Has Oncogenic Functions in Pancreatic Ductal Adenocarcinoma Cells
The cancer secretome is a rich repository of useful information for both cancer biology and clinical oncology. A better understanding of cancer secretome is particularly relevant for pancreatic ductal adenocarcinoma (PDAC), whose extremely high mortality
Giovanna Butera +9 more
doaj +1 more source
Sequence-directed activation of human oncogenes.
Sequence-directed activation of human ...
Lavanya. Lall (7958528)
core +3 more sources

