Results 31 to 40 of about 30,889 (150)

Ultrabright gap-enhanced Raman tags for high-speed bioimaging

open access: yesNature Communications, 2019
The speed of surface-enhanced Raman spectroscopy (SERS) imaging is generally limited due to low Raman signals. Here, the authors develop bright gap-enhanced Raman tags with external hot spots and demonstrate their use in fast near-infrared bioimaging.
Yuqing Zhang   +4 more
doaj   +1 more source

Regulation of Endoplasmic Reticulum–Mitochondria Ca2+ Transfer and Its Importance for Anti-Cancer Therapies

open access: yesFrontiers in Oncology, 2017
Inter-organelle membrane contact sites are emerging as major sites for the regulation of intracellular Ca2+ concentration and distribution. Here, extracellular stimuli operate on a wide array of channels, pumps, and ion exchangers to redistribute ...
Gaia Pedriali   +6 more
doaj   +1 more source

Oncogenic Processes [PDF]

open access: yesBioMed Research International, 2014
No abstract available.
Rita de Cassia Stocco   +3 more
openaire   +4 more sources

Novel oncogenes and tumor suppressor genes in hepatocellular carcinoma [PDF]

open access: yes, 2021
Hepatocellular carcinoma (HCC) is a very deadly disease. HCC initiation and progression involve multiple genetic events, including the activation of proto-oncogenes and disruption of the function of specific tumor suppressor genes.
Breslin S J, Peter   +5 more
core   +1 more source

Fast Prototyping Microfluidics: Integrating Droplet Digital Lamp for Absolute Quantification of Cancer Biomarkers

open access: yesSensors, 2020
Microfluidic (MF) advancements have been leveraged toward the development of state-of-the-art platforms for molecular diagnostics, where isothermal amplification schemes allow for further simplification of DNA detection and quantification protocols.
Beatriz Oliveira   +6 more
doaj   +1 more source

Targeting C-myc G-Quadruplex: Dual Recognition by Aminosugar-Bisbenzimidazoles with Varying Linker Lengths

open access: yesMolecules, 2013
G-quadruplexes are therapeutically important biological targets. In this report, we present biophysical studies of neomycin-Hoechst 33258 conjugates binding to a G-quadruplex derived from the C-myc promoter sequence.
Nihar Ranjan, Dev P. Arya
doaj   +1 more source

Proto‐oncogenes and oncogenes in epidermal neoplasia [PDF]

open access: yesExperimental Dermatology, 1995
Abstract This review briefly will focus on the role of selected proto‐onco‐genes and their activated forms during the regulation of cell proliferation, cell death and tumor formation in the epidermis. In addition, the multiple and complex functions of these proteins in normal as well as transformed cells will be discussed.
M M, Simon, G, Sliutz, T A, Luger
openaire   +2 more sources

Oncogenes

open access: yesScandinavian Journal of Gastroenterology, 1985
The central problem in cancer therapy is the poor selectivity of current systemic agents against the common solid tumours. The demonstration that unique segments of DNA, constant in location and conserved in evolution are involved in growth control opens new avenues for basic and clinical research.
  +8 more sources

The Mutant p53-Driven Secretome Has Oncogenic Functions in Pancreatic Ductal Adenocarcinoma Cells

open access: yesBiomolecules, 2020
The cancer secretome is a rich repository of useful information for both cancer biology and clinical oncology. A better understanding of cancer secretome is particularly relevant for pancreatic ductal adenocarcinoma (PDAC), whose extremely high mortality
Giovanna Butera   +9 more
doaj   +1 more source

Sequence-directed activation of human oncogenes.

open access: yes, 1998
Sequence-directed activation of human ...
Lavanya. Lall (7958528)
core   +3 more sources

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