Results 51 to 60 of about 30,889 (150)
RAS oncogenes direct metastasis.
, 2017 RAS genes are cardinal driver oncogenes frequently and differentially mutated across bodily tumors. Their tumorigenic potential has been mainly ascribed to autonomous promotion of tumor cell proliferation and survival. However, recent evidence shows that
Spella, M. +7 more
core +1 more source
, 1990 Myogenic cells can be transformed in vitro by the introduction of several exogenous viral oncogenes. Transformed myoblasts are prevented from terminal differentiation into myotubes by the continuous expression of oncogenes such as myc and src, chosen as ...
Falcone G +3 more
core
Cross-species comparison of CpG density in the promoter regions of protein kinase oncogenes
, 2015 In this report, we investigated CpG density occurred in promoter regions (PRs) and downstream flanking regions (DFR) of 61 human protein kinase oncogenes (PKOs), together with other three species: chimpanzee, mouse and horse.
Pioth, Gabriel G. +2 more
core +1 more source
An oncogene is a mutated form of a normal cellular gene – called a proto-oncogene – that contributes to the development of a cancer. Proto-oncogenes typically regulate cell growth and cell differentiation.
حسینی اصل, سید سعید
core
Advances on Driver Oncogenes of Lung Adenocarcinoma
, 2013 The adenocarcinoma of the lung has recently shown peculiar molecular characteristics, which relate with both carcinogenesis and response to targeted drugs.
Jinghui WANG, Zongde ZHANG, Shucai ZHANG
core +1 more source
Role of STAT3 in in vitro transformation triggered by TRK oncogenes. [PDF]
, 2010 TRK oncoproteins are chimeric versions of the NTRK1/NGF receptor and display constitutive tyrosine kinase activity leading to transformation of NIH3T3 cells and neuronal differentiation of PC12 cells.
Claudia Miranda +13 more
core +1 more source
Revista Cubana de Estomatología, 2016 Introduction: oral cancer is a disease with high morbidity and mortality, associated with risk factors whose complex interplay is subject to scientific debate.
Pedro Antonio Miguel Cruz +3 more
doaj
Identified scrib− cooperating oncogenes.
, 2013 Identified scrib− cooperating oncogenes.
Karen R. Goulding (434917) +12 more
core +1 more source
Genome wide analysis of oral squamous cell carcinoma.
, 2009 [[abstract]]Oncogenes serve as specific and unique targets for drug intervention to treat cancer, as their activation (amplification and activating mutation) is essential for tumor development.
I-Wen Chiu
core