Results 151 to 160 of about 171,834 (303)

A testis-specific E3 ubiquitin ligase complex governs spermiogenesis and male fertility. [PDF]

Nat Commun
Wu T, Tu C, Feng Y, Qu W, Chen J, Wu H, Gao W, Xu B, Yu X, Bao M, Xu J, Zhou N, Hu H, Jiang B, Xie Q, Meng L, Tan C, Lin G, Shen C, Chen X, Guo Y, Zhou T, Liang Y, Hua R, Cao Y, Liu M, Yu J, Huang X, Tan YQ, Zheng B.   +29 more
europepmc   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

Exploring the Mechanisms, Biomarkers, and Therapeutic Targets of TRIM Family in Gastrointestinal Cancer

Drug Design, Development and Therapy
Chunyan Weng,1,* Rijuan Jin,1,* Xiaoliang Jin,1,* Zimei Yang,1,* Chenghai He,1,2 Qiuhua Zhang,1 Jingli Xu,1,3 Bin Lv1 1Department of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang ...
Weng C, Jin R, Jin X, Yang Z, He C, Zhang Q, Xu J, Lv B   +7 more
doaj  

E3 Ubiquitin Ligase Nedd4-2 Exacerbates Seizure-Induced Mitochondrial Defects in an Alzheimer's Disease Mouse Model. [PDF]

J Neurochem
Wang Y, Zhu J, Lizarazo S, Lee KY, Wong O, Azim S, Yook Y, Kumar V, Tsai NP.   +8 more
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase UBR5 [PDF]

, 2020
openaire   +1 more source

The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors. Pathogenic mutations in UBE3B result in neurodevelopmental disease, including intellectual disability, lack of speech, and ASD.
Shayal Vashisth, Aleya Shedd, Ariel Aiken, Solmi Cheon, Josh Bandopadhay, Kiran Kaur, Kimberly M. Huber, Maria H. Chahrour   +7 more
wiley   +1 more source

Construction of a robust sepsis prognostic classifier based on E3 ubiquitin ligase-related genes. [PDF]

Front Mol Biosci
Xue H, Chen L, Zhao X, Zhu F.
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase RNF43 [PDF]

, 2020
openaire   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

E3 ubiquitin ligase NEDD4 inhibits PEDV infection through ubiquitination and degradation of the viral primase NSP8. [PDF]

J Virol
Guo X, Zhao X, He J, Lu Y, Jin S, Ma Z, Li Z, Zheng Z, Li Y, Feng Y, Xu L, Liu X, Zhang J, Wei Z, Zheng H, Xiao S.   +15 more
europepmc   +1 more source