Results 181 to 190 of about 171,834 (303)
Journal of Clinical Laboratory Analysis, EarlyView.Our findings indicated that the rs4245739 A>C polymorphism was not associated with BC risk in the Bangladeshi population, whereas the rs1380576 C>G polymorphism was significantly associated with BC risk. This study provides new insights into the genetic factors influencing breast cancer susceptibility in the Bangladeshi population, highlighting the ...
J. M. Aousiful Islam +7 more
wiley +1 more source
The E3 ubiquitin ligase Trip12 semi-selectively attenuates Wnt signaling. [PDF]
iScienceEnsing J +8 more
europepmc +1 more source
Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa +2 more
wiley +1 more source
Balancing rice blast resistance and growth through suppression of the E3 ubiquitin ligase OsRING80. [PDF]
Plant PhysiolHou X +9 more
europepmc +1 more source
Medicine Bulletin, EarlyView.ABSTRACT Background Cisplatin (CIS) is a widely used broad‐spectrum anticancer agent, but its clinical application is often limited by severe adverse effects, including skeletal muscle atrophy, which compromises patients' quality of life and treatment efficacy.
Hao‐Zhe Wang +10 more
wiley +1 more source
Functional and structural analyses of UbcH5 mutants with enhanced binding to the E3 ubiquitin ligase CHIP. [PDF]
Biochem Biophys Res CommunManage MM, Nix JC, Page RC.
europepmc +1 more source