Results 11 to 20 of about 3,528 (86)

Residue-Specific Signatures of Structural Water Identified by Dissolution Dynamic Nuclear Polarization with UV-Generated Radicals. [PDF]

open access: yesAngew Chem Int Ed Engl
Structural water molecules in proteins are notoriously hard to detect in solution. Hyperpolarized water with UV radicals as polarizing agents provides the sensitivity and resolution to detect residue‐specific signatures of structural water with NMR spectroscopy.
Hecker F   +3 more
europepmc   +3 more sources

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

open access: yesAdvanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang   +6 more
wiley   +1 more source

Supplier Environmental Assessment in Sustainability Reporting: Evidence From Top ESG‐Performing Brazilian Firms

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines the maturity of supplier‐related environmental disclosures in sustainability reports of top environmental, social, and governance (ESG)‐performing Brazilian companies. A content analysis of 67 reports from firms listed on the Corporate Sustainability Index (CSI) was conducted using the CRITIC method to weight disclosure ...
João Vyctor Brás dos Santos   +6 more
wiley   +1 more source

S3 guideline diagnostics and therapy in alopecia areata – Part 2: Therapy, psychosocial and cosmetic support

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary This second part of the S3 guideline on the diagnosis and treatment of alopecia areata (AA), presents key recommendations on topical and systemic therapy, quality of life and support services. The first part of the guideline, published separately, covers the definition and content of epidemiology and diagnosis as well as comorbidities, risk and
Ulrike Blume‐Peytavi   +13 more
wiley   +1 more source

Dynamic Trust Formation in AI‐Enabled Automation: A Longitudinal Case Study of an Advanced Driver Assistance System

open access: yesInformation Systems Journal, EarlyView.
ABSTRACT Artificial intelligence (AI)–enabled automation is often utilised in systems that perform human tasks. While useful, these technologies pose a risk of adverse consequences in the case of AI failures as they operate in open environments, learn and are subject to continuous updates.
Kari M. Koskinen   +3 more
wiley   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque embryonic brain histology datasets

open access: yesJournal of Anatomy, EarlyView.
We introduce the MacBrain Resource Center (MBRC) Collections of rhesus macaque embryonic brain tissue. Here, we illustrate histo‐ and immunohistology from our dynamically growing Collection 6, which currently contains >10,000 zoomable and downloadable images from n = 14 male and female embryos from early to late in gestation.
Valeria Mendoza‐Silva   +11 more
wiley   +1 more source

General Predictions for the Effects of Warming on Competition

open access: yesEcology Letters, Volume 29, Issue 6, June 2026.
We combined two major theories in ecology to investigate whether warming may have general effects on competition for shared resources. We found that species' niche and fitness differences both decreased with warming, and that competing consumers with highly asymmetrical thermal traits underwent the most dramatic competitive shifts under warming ...
Kaleigh E. Davis   +5 more
wiley   +1 more source

Arabidopsis acclimation to daily environmental fluctuations converts a defense response regulator into a susceptibility factor toward Sclerotinia

open access: yesNew Phytologist, Volume 250, Issue 4, Page 2516-2534, May 2026.
Summary Acclimation enables plants to adjust to immediate environmental fluctuations and is therefore key to the resilience of plant disease resistance in a time of climate change. Here, we report on the acclimation of Arabidopsis thaliana quantitative immune responses against the fungal pathogen Sclerotinia sclerotiorum to daily environmental ...
Marie Didelon   +6 more
wiley   +1 more source

A Novel Topical Emollient Plus for Canine Atopic Dermatitis: A Clinical Trial Assessing Efficacy and User Acceptance

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 293-305, April 2026.
Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes   +8 more
wiley   +1 more source

Screening and Diagnosis of Malnutrition in Individuals With Obesity: A Scoping Review of Current Methods

open access: yesObesity Reviews, Volume 27, Issue 3, March 2026.
ABSTRACT Rationale The global rise in obesity presents a major public health challenge, commonly associated with an increased risk of noncommunicable diseases. Paradoxically, individuals with obesity, particularly older adults and those with comorbidities, are also at risk of malnutrition.
Natasha Nalucha Mwala   +6 more
wiley   +1 more source

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